| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 696 | 111 | 71 | 0.298 | 0.368 | 2.26 | 2B |
| Jacoby Ellsbury | 680 | 90 | 61 | 0.297 | 0.347 | -0.61 | CF |
| Jason Bay | 624 | 103 | 117 | 0.264 | 0.385 | 7.99 | LF |
| David Ortiz | 614 | 79 | 97 | 0.238 | 0.332 | 3.61 | DH |
| Kevin Youkilis | 573 | 98 | 91 | 0.305 | 0.414 | 5.97 | 1B-3B |
| J.D. Drew | 536 | 83 | 65 | 0.276 | 0.390 | 2.56 | RF |
| Mike Lowell | 476 | 55 | 75 | 0.290 | 0.336 | 2.12 | 3B |
| Jason Varitek | 419 | 41 | 52 | 0.209 | 0.313 | -0.38 | CR |
| Nick Green | 309 | 34 | 36 | 0.236 | 0.301 | -0.13 | SS |
| Victor Martinez | 224 | 28 | 36 | 0.332 | 0.402 | 1.30 | CR-1B |
| Rocco Baldelli | 161 | 23 | 23 | 0.259 | 0.317 | 0.93 | RF |
| Alex Gonzalez | 147 | 24 | 15 | 0.279 | 0.293 | 0.54 | SS |
| Julio Lugo | 123 | 16 | 8 | 0.284 | 0.350 | -0.46 | 2B-SS |
| George Kottaras | 105 | 14 | 10 | 0.220 | 0.295 | -0.02 | CR |
| Jeff Bailey | 91 | 14 | 10 | 0.208 | 0.330 | 0.32 | 1B |
| Casey Kotchman | 87 | 7 | 7 | 0.215 | 0.287 | -0.64 | 1B |
| Mark Kotsay | 79 | 5 | 5 | 0.257 | 0.291 | -0.86 | 1B |
| Jed Lowrie | 69 | 2 | 7 | 0.145 | 0.203 | -0.73 | SS |
| Josh Reddick | 59 | 5 | 4 | 0.179 | 0.220 | -0.48 | LF-RF |
| Adam LaRoche | 19 | 2 | 3 | 0.263 | 0.263 | 0.06 | 1B |
| Chris Woodward | 16 | 0 | 0 | 0.083 | 0.312 | -0.39 | 3B |
| Brian Anderson | 14 | 2 | 2 | 0.167 | 0.214 | 0.08 | CF |
| Jonathan Van Every | 13 | 1 | 3 | 0.364 | 0.462 | 0.11 | X |
| Aaron Bates | 12 | 1 | 2 | 0.364 | 0.417 | 0.02 | X |
| Joey Gathright | 8 | 1 | 0 | 0.500 | 0.500 | -0.09 | CF |
| Chris Carter | 6 | 0 | 1 | 0.000 | 0.000 | -0.04 | X |
| Gil Velazquez | 3 | 0 | 0 | 0.000 | 0.333 | -0.07 | X |
| Dusty Brown | 1 | 0 | 0 | 0.000 | 0.000 | -0.02 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Josh Beckett | 207.3 | 3.78 | 31 | 0 | X | 2.69 |
| Jon Lester | 197.0 | 3.52 | 31 | 0 | X | 3.74 |
| Brad Penny | 131.7 | 5.61 | 24 | 0 | X | -3.91 |
| Tim Wakefield | 129.7 | 4.58 | 21 | 0 | X | -0.75 |
| Clay Buchholz | 89.0 | 3.74 | 15 | 0 | X | 1.23 |
| Justin Masterson | 72.0 | 4.25 | 6 | 25 | X | 0.14 |
| Ramon Ramirez | 67.7 | 2.93 | 0 | 68 | X | 2.22 |
| Jonathan Papelbon | 66.0 | 1.91 | 0 | 64 | X | 3.73 |
| Hideki Okajima | 61.0 | 3.39 | 0 | 68 | X | 1.34 |
| Manny Delcarmen | 59.7 | 4.83 | 0 | 64 | X | -0.69 |
| Takashi Saito | 54.7 | 2.47 | 0 | 55 | X | 2.38 |
| Daisuke Matsuzaka | 53.3 | 6.07 | 11 | 0 | X | -2.17 |
| Daniel Bard | 47.3 | 3.80 | 0 | 46 | X | 0.58 |
| John Smoltz | 40.0 | 8.10 | 8 | 0 | X | -3.52 |
| Paul Byrd | 31.0 | 5.81 | 6 | 0 | X | -1.07 |
| Junichi Tazawa | 25.3 | 7.46 | 4 | 2 | X | -1.85 |
| Michael Bowden | 13.3 | 10.80 | 1 | 6 | X | -2.01 |
| Hunter Jones | 12.7 | 9.24 | 0 | 11 | X | -1.45 |
| Billy Wagner | 12.0 | 2.25 | 0 | 13 | X | 0.58 |
| Javier Lopez | 11.7 | 9.26 | 0 | 14 | X | -1.34 |
| Fernando Cabrera | 5.0 | 9.00 | 0 | 5 | X | -0.54 |
| Enrique Gonzalez | 3.7 | 4.91 | 0 | 2 | X | -0.05 |
| Billy Traber | 3.7 | 14.73 | 0 | 1 | X | -0.89 |
| Dustin Richardson | 2.3 | 0.00 | 0 | 2 | X | 0.24 |
| Nick Green | 2.0 | 0.00 | 0 | 1 | X | 0.20 |
| Dusty Brown | 1.0 | 9.00 | 0 | 1 | X | -0.11 |
| Jonathan Van Every | 0.7 | 0.00 | 0 | 1 | X | 0.07 |
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