| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 691 | 110 | 71 | 0.295 | 0.366 | 2.26 | 2B |
| Jacoby Ellsbury | 675 | 89 | 61 | 0.296 | 0.347 | -0.60 | CF |
| Jason Bay | 620 | 101 | 117 | 0.266 | 0.384 | 7.87 | LF |
| David Ortiz | 606 | 78 | 96 | 0.237 | 0.332 | 3.59 | DH |
| Kevin Youkilis | 568 | 97 | 90 | 0.305 | 0.414 | 5.87 | 1B-3B |
| J.D. Drew | 532 | 82 | 62 | 0.272 | 0.387 | 2.23 | RF |
| Mike Lowell | 476 | 55 | 75 | 0.290 | 0.336 | 2.12 | 3B |
| Jason Varitek | 419 | 41 | 52 | 0.209 | 0.313 | -0.39 | CR |
| Nick Green | 309 | 34 | 36 | 0.236 | 0.301 | -0.14 | SS |
| Victor Martinez | 219 | 28 | 35 | 0.333 | 0.402 | 1.31 | CR-1B |
| Rocco Baldelli | 157 | 23 | 23 | 0.259 | 0.318 | 1.03 | RF |
| Alex Gonzalez | 142 | 24 | 15 | 0.281 | 0.296 | 0.65 | SS |
| Julio Lugo | 123 | 16 | 8 | 0.284 | 0.350 | -0.46 | 2B-SS |
| George Kottaras | 102 | 14 | 10 | 0.227 | 0.304 | 0.05 | CR |
| Jeff Bailey | 91 | 14 | 10 | 0.208 | 0.330 | 0.32 | 1B |
| Casey Kotchman | 79 | 7 | 7 | 0.222 | 0.291 | -0.44 | 1B |
| Mark Kotsay | 79 | 5 | 5 | 0.257 | 0.291 | -0.86 | 1B |
| Jed Lowrie | 66 | 2 | 7 | 0.153 | 0.212 | -0.65 | SS |
| Josh Reddick | 54 | 5 | 4 | 0.196 | 0.241 | -0.36 | LF-RF |
| Adam LaRoche | 19 | 2 | 3 | 0.263 | 0.263 | 0.06 | 1B |
| Chris Woodward | 13 | 0 | 0 | 0.100 | 0.308 | -0.31 | 3B |
| Jonathan Van Every | 13 | 1 | 3 | 0.364 | 0.462 | 0.11 | X |
| Brian Anderson | 13 | 2 | 2 | 0.182 | 0.231 | 0.11 | CF |
| Aaron Bates | 12 | 1 | 2 | 0.364 | 0.417 | 0.02 | X |
| Chris Carter | 6 | 0 | 1 | 0.000 | 0.000 | -0.04 | X |
| Joey Gathright | 4 | 1 | 0 | 0.500 | 0.500 | 0.01 | CF |
| Gil Velazquez | 3 | 0 | 0 | 0.000 | 0.333 | -0.07 | X |
| Dusty Brown | 1 | 0 | 0 | 0.000 | 0.000 | -0.02 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Josh Beckett | 207.3 | 3.78 | 31 | 0 | X | 2.72 |
| Jon Lester | 197.0 | 3.52 | 31 | 0 | X | 3.77 |
| Brad Penny | 131.7 | 5.61 | 24 | 0 | X | -3.89 |
| Tim Wakefield | 126.7 | 4.33 | 20 | 0 | X | 0.01 |
| Clay Buchholz | 84.0 | 3.21 | 14 | 0 | X | 2.20 |
| Justin Masterson | 72.0 | 4.25 | 6 | 25 | X | 0.15 |
| Ramon Ramirez | 66.7 | 2.97 | 0 | 67 | X | 2.13 |
| Jonathan Papelbon | 65.0 | 1.94 | 0 | 63 | X | 3.64 |
| Hideki Okajima | 60.0 | 3.30 | 0 | 67 | X | 1.45 |
| Manny Delcarmen | 58.7 | 4.60 | 0 | 63 | X | -0.36 |
| Takashi Saito | 53.7 | 2.35 | 0 | 54 | X | 2.49 |
| Daisuke Matsuzaka | 53.3 | 6.07 | 11 | 0 | X | -2.16 |
| Daniel Bard | 47.3 | 3.80 | 0 | 46 | X | 0.59 |
| John Smoltz | 40.0 | 8.10 | 8 | 0 | X | -3.51 |
| Paul Byrd | 31.0 | 5.81 | 6 | 0 | X | -1.06 |
| Junichi Tazawa | 25.3 | 7.46 | 4 | 2 | X | -1.85 |
| Michael Bowden | 13.3 | 10.80 | 1 | 6 | X | -2.01 |
| Javier Lopez | 11.7 | 9.26 | 0 | 14 | X | -1.34 |
| Hunter Jones | 11.7 | 10.03 | 0 | 10 | X | -1.55 |
| Billy Wagner | 11.0 | 2.45 | 0 | 12 | X | 0.48 |
| Fernando Cabrera | 4.0 | 4.50 | 0 | 4 | X | -0.02 |
| Enrique Gonzalez | 3.7 | 4.91 | 0 | 2 | X | -0.05 |
| Billy Traber | 3.7 | 14.73 | 0 | 1 | X | -0.89 |
| Nick Green | 2.0 | 0.00 | 0 | 1 | X | 0.20 |
| Dustin Richardson | 1.3 | 0.00 | 0 | 1 | X | 0.13 |
| Jonathan Van Every | 0.7 | 0.00 | 0 | 1 | X | 0.07 |
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