| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 655 | 104 | 66 | 0.296 | 0.363 | 2.06 | 2B |
| Jacoby Ellsbury | 638 | 83 | 56 | 0.303 | 0.351 | -0.78 | CF |
| Jason Bay | 590 | 96 | 112 | 0.268 | 0.388 | 7.62 | LF |
| David Ortiz | 572 | 73 | 85 | 0.232 | 0.325 | 2.80 | DH |
| Kevin Youkilis | 539 | 94 | 86 | 0.309 | 0.417 | 5.91 | 1B-3B |
| J.D. Drew | 512 | 81 | 62 | 0.266 | 0.383 | 2.68 | RF |
| Mike Lowell | 454 | 54 | 74 | 0.295 | 0.337 | 2.50 | 3B |
| Jason Varitek | 409 | 41 | 52 | 0.211 | 0.315 | -0.09 | CR |
| Nick Green | 309 | 34 | 36 | 0.236 | 0.301 | -0.10 | SS |
| Victor Martinez | 187 | 23 | 31 | 0.331 | 0.401 | 1.16 | CR-1B |
| Rocco Baldelli | 150 | 21 | 23 | 0.255 | 0.313 | 1.00 | RF |
| Julio Lugo | 123 | 16 | 8 | 0.284 | 0.350 | -0.44 | 2B-SS |
| Alex Gonzalez | 117 | 19 | 15 | 0.295 | 0.299 | 0.75 | SS |
| George Kottaras | 102 | 14 | 10 | 0.227 | 0.304 | 0.06 | CR |
| Jeff Bailey | 91 | 14 | 10 | 0.208 | 0.330 | 0.33 | 1B |
| Mark Kotsay | 79 | 5 | 5 | 0.257 | 0.291 | -0.85 | 1B |
| Casey Kotchman | 66 | 6 | 7 | 0.230 | 0.288 | -0.23 | 1B |
| Jed Lowrie | 64 | 2 | 7 | 0.158 | 0.219 | -0.60 | SS |
| Josh Reddick | 46 | 5 | 4 | 0.233 | 0.283 | -0.16 | LF-RF |
| Adam LaRoche | 19 | 2 | 3 | 0.263 | 0.263 | 0.07 | 1B |
| Jonathan Van Every | 13 | 1 | 3 | 0.364 | 0.462 | 0.11 | X |
| Aaron Bates | 12 | 1 | 2 | 0.364 | 0.417 | 0.03 | X |
| Chris Woodward | 10 | 0 | 0 | 0.000 | 0.300 | -0.24 | 3B |
| Brian Anderson | 10 | 1 | 2 | 0.222 | 0.200 | 0.07 | CF |
| Chris Carter | 6 | 0 | 1 | 0.000 | 0.000 | -0.04 | X |
| Joey Gathright | 4 | 1 | 0 | 0.500 | 0.500 | 0.01 | CF |
| Gil Velazquez | 3 | 0 | 0 | 0.000 | 0.333 | -0.07 | X |
| Dusty Brown | 1 | 0 | 0 | 0.000 | 0.000 | -0.02 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Josh Beckett | 201.3 | 3.80 | 30 | 0 | X | 2.37 |
| Jon Lester | 194.7 | 3.33 | 30 | 0 | X | 4.43 |
| Brad Penny | 131.7 | 5.61 | 24 | 0 | X | -4.00 |
| Tim Wakefield | 121.7 | 4.22 | 19 | 0 | X | 0.25 |
| Clay Buchholz | 77.3 | 3.49 | 13 | 0 | X | 1.47 |
| Justin Masterson | 72.0 | 4.25 | 6 | 25 | X | 0.09 |
| Ramon Ramirez | 64.0 | 2.67 | 0 | 64 | X | 2.44 |
| Jonathan Papelbon | 64.0 | 1.97 | 0 | 62 | X | 3.49 |
| Hideki Okajima | 59.0 | 3.36 | 0 | 66 | X | 1.31 |
| Manny Delcarmen | 55.3 | 4.07 | 0 | 59 | X | 0.31 |
| Takashi Saito | 51.7 | 2.44 | 0 | 52 | X | 2.25 |
| Daisuke Matsuzaka | 46.3 | 6.80 | 10 | 0 | X | -2.70 |
| Daniel Bard | 45.7 | 3.35 | 0 | 43 | X | 1.02 |
| John Smoltz | 40.0 | 8.10 | 8 | 0 | X | -3.54 |
| Junichi Tazawa | 25.3 | 7.46 | 4 | 2 | X | -1.87 |
| Paul Byrd | 18.7 | 5.79 | 4 | 0 | X | -0.65 |
| Javier Lopez | 11.7 | 9.26 | 0 | 14 | X | -1.35 |
| Hunter Jones | 9.0 | 8.00 | 0 | 8 | X | -0.78 |
| Billy Wagner | 8.3 | 2.16 | 0 | 9 | X | 0.42 |
| Michael Bowden | 6.0 | 10.50 | 0 | 3 | X | -0.87 |
| Fernando Cabrera | 4.0 | 4.50 | 0 | 4 | X | -0.02 |
| Enrique Gonzalez | 3.7 | 4.91 | 0 | 2 | X | -0.05 |
| Billy Traber | 3.7 | 14.73 | 0 | 1 | X | -0.89 |
| Nick Green | 2.0 | 0.00 | 0 | 1 | X | 0.20 |
| Jonathan Van Every | 0.7 | 0.00 | 0 | 1 | X | 0.07 |
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