| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 593 | 95 | 60 | 0.296 | 0.368 | 1.95 | 2B |
| Jacoby Ellsbury | 576 | 73 | 49 | 0.295 | 0.340 | -1.11 | CF |
| Jason Bay | 540 | 85 | 98 | 0.258 | 0.383 | 6.17 | LF |
| David Ortiz | 526 | 63 | 80 | 0.225 | 0.317 | 2.31 | DH |
| Kevin Youkilis | 494 | 86 | 81 | 0.316 | 0.421 | 5.60 | 1B-3B |
| J.D. Drew | 468 | 73 | 55 | 0.269 | 0.385 | 2.13 | RF |
| Mike Lowell | 413 | 50 | 67 | 0.299 | 0.341 | 2.31 | 3B |
| Jason Varitek | 381 | 39 | 49 | 0.217 | 0.325 | 0.03 | CR |
| Nick Green | 304 | 34 | 35 | 0.235 | 0.299 | -0.10 | SS |
| Rocco Baldelli | 139 | 20 | 22 | 0.262 | 0.324 | 1.05 | RF |
| Victor Martinez | 139 | 18 | 21 | 0.322 | 0.403 | 0.74 | CR-1B |
| Julio Lugo | 123 | 16 | 8 | 0.284 | 0.350 | -0.45 | 2B-SS |
| George Kottaras | 101 | 14 | 10 | 0.230 | 0.307 | 0.08 | CR |
| Jeff Bailey | 91 | 14 | 10 | 0.208 | 0.330 | 0.32 | 1B |
| Mark Kotsay | 79 | 5 | 5 | 0.257 | 0.291 | -0.86 | 1B |
| Alex Gonzalez | 72 | 11 | 8 | 0.278 | 0.278 | 0.26 | SS |
| Jed Lowrie | 63 | 2 | 7 | 0.143 | 0.206 | -0.58 | SS |
| Casey Kotchman | 44 | 6 | 5 | 0.205 | 0.295 | 0.09 | 1B |
| Josh Reddick | 35 | 2 | 2 | 0.182 | 0.229 | -0.43 | LF-RF |
| Adam LaRoche | 19 | 2 | 3 | 0.263 | 0.263 | 0.07 | 1B |
| Jonathan Van Every | 13 | 1 | 3 | 0.364 | 0.462 | 0.11 | X |
| Aaron Bates | 12 | 1 | 2 | 0.364 | 0.417 | 0.03 | X |
| Chris Woodward | 9 | 0 | 0 | 0.000 | 0.333 | -0.22 | 3B |
| Brian Anderson | 8 | 0 | 1 | 0.143 | 0.125 | -0.09 | CF |
| Chris Carter | 6 | 0 | 1 | 0.000 | 0.000 | -0.04 | X |
| Gil Velazquez | 3 | 0 | 0 | 0.000 | 0.333 | -0.07 | X |
| Joey Gathright | 2 | 1 | 0 | 0.500 | 0.500 | 0.06 | CF |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Josh Beckett | 181.3 | 3.87 | 27 | 0 | X | 1.87 |
| Jon Lester | 173.7 | 3.58 | 27 | 0 | X | 2.99 |
| Brad Penny | 131.7 | 5.61 | 24 | 0 | X | -3.97 |
| Tim Wakefield | 115.7 | 4.12 | 18 | 0 | X | 0.51 |
| Justin Masterson | 72.0 | 4.25 | 6 | 25 | X | 0.11 |
| Jonathan Papelbon | 58.7 | 1.84 | 0 | 57 | X | 3.38 |
| Ramon Ramirez | 58.3 | 2.93 | 0 | 58 | X | 1.88 |
| Clay Buchholz | 57.3 | 4.40 | 10 | 0 | X | -0.11 |
| Manny Delcarmen | 54.0 | 3.67 | 0 | 56 | X | 0.81 |
| Hideki Okajima | 53.7 | 3.19 | 0 | 60 | X | 1.41 |
| Takashi Saito | 48.7 | 2.59 | 0 | 49 | X | 1.96 |
| Daniel Bard | 42.3 | 3.40 | 0 | 38 | X | 0.90 |
| John Smoltz | 40.0 | 8.10 | 8 | 0 | X | -3.53 |
| Daisuke Matsuzaka | 35.0 | 8.23 | 8 | 0 | X | -3.20 |
| Junichi Tazawa | 25.3 | 7.46 | 4 | 2 | X | -1.86 |
| Javier Lopez | 11.7 | 9.26 | 0 | 14 | X | -1.35 |
| Hunter Jones | 9.0 | 8.00 | 0 | 8 | X | -0.77 |
| Paul Byrd | 8.3 | 7.56 | 2 | 0 | X | -0.63 |
| Michael Bowden | 4.0 | 15.75 | 0 | 2 | X | -1.07 |
| Fernando Cabrera | 4.0 | 4.50 | 0 | 4 | X | -0.02 |
| Billy Traber | 3.7 | 14.73 | 0 | 1 | X | -0.89 |
| Enrique Gonzalez | 3.7 | 4.91 | 0 | 2 | X | -0.05 |
| Billy Wagner | 3.0 | 0.00 | 0 | 3 | X | 0.30 |
| Nick Green | 2.0 | 0.00 | 0 | 1 | X | 0.20 |
| Jonathan Van Every | 0.7 | 0.00 | 0 | 1 | X | 0.07 |
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