| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 547 | 91 | 57 | 0.303 | 0.375 | 2.29 | 2B |
| Jacoby Ellsbury | 531 | 68 | 45 | 0.293 | 0.337 | -1.00 | CF |
| Jason Bay | 505 | 81 | 90 | 0.257 | 0.382 | 5.72 | LF |
| David Ortiz | 485 | 57 | 76 | 0.226 | 0.320 | 2.21 | DH |
| Kevin Youkilis | 453 | 78 | 73 | 0.310 | 0.422 | 4.88 | 1B-3B |
| J.D. Drew | 432 | 66 | 49 | 0.260 | 0.375 | 1.61 | RF |
| Mike Lowell | 392 | 48 | 65 | 0.303 | 0.347 | 2.37 | 3B |
| Jason Varitek | 365 | 38 | 48 | 0.223 | 0.332 | 0.19 | CR |
| Nick Green | 301 | 33 | 35 | 0.230 | 0.296 | -0.15 | SS |
| Rocco Baldelli | 129 | 18 | 20 | 0.267 | 0.333 | 0.86 | RF |
| Julio Lugo | 123 | 16 | 8 | 0.284 | 0.350 | -0.46 | 2B-SS |
| Victor Martinez | 99 | 13 | 16 | 0.322 | 0.394 | 0.65 | CR-1B |
| George Kottaras | 99 | 14 | 9 | 0.224 | 0.303 | 0.02 | CR |
| Jeff Bailey | 91 | 14 | 10 | 0.208 | 0.330 | 0.32 | 1B |
| Mark Kotsay | 79 | 5 | 5 | 0.257 | 0.291 | -0.86 | 1B |
| Jed Lowrie | 63 | 2 | 7 | 0.143 | 0.206 | -0.58 | SS |
| Alex Gonzalez | 36 | 6 | 4 | 0.250 | 0.250 | 0.18 | SS |
| Casey Kotchman | 36 | 6 | 4 | 0.250 | 0.333 | 0.18 | 1B |
| Josh Reddick | 33 | 2 | 2 | 0.188 | 0.212 | -0.38 | LF-RF |
| Adam LaRoche | 19 | 2 | 3 | 0.263 | 0.263 | 0.06 | 1B |
| Jonathan Van Every | 13 | 1 | 3 | 0.364 | 0.462 | 0.11 | X |
| Aaron Bates | 12 | 1 | 2 | 0.364 | 0.417 | 0.02 | X |
| Chris Woodward | 7 | 0 | 0 | 0.000 | 0.429 | -0.17 | 3B |
| Brian Anderson | 7 | 0 | 1 | 0.167 | 0.143 | -0.06 | CF |
| Chris Carter | 6 | 0 | 1 | 0.000 | 0.000 | -0.04 | X |
| Gil Velazquez | 3 | 0 | 0 | 0.000 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Josh Beckett | 170.3 | 3.65 | 25 | 0 | X | 2.69 |
| Jon Lester | 161.0 | 3.58 | 25 | 0 | X | 2.80 |
| Brad Penny | 131.7 | 5.61 | 24 | 0 | X | -3.94 |
| Tim Wakefield | 108.7 | 4.31 | 17 | 0 | X | 0.04 |
| Justin Masterson | 72.0 | 4.25 | 6 | 25 | X | 0.12 |
| Ramon Ramirez | 55.7 | 2.59 | 0 | 55 | X | 2.26 |
| Jonathan Papelbon | 53.0 | 2.04 | 0 | 52 | X | 2.83 |
| Hideki Okajima | 52.3 | 2.75 | 0 | 56 | X | 1.92 |
| Manny Delcarmen | 49.3 | 3.83 | 0 | 51 | X | 0.57 |
| Takashi Saito | 45.0 | 2.80 | 0 | 45 | X | 1.60 |
| Clay Buchholz | 43.0 | 5.02 | 8 | 0 | X | -0.70 |
| John Smoltz | 40.0 | 8.10 | 8 | 0 | X | -3.52 |
| Daniel Bard | 38.3 | 3.76 | 0 | 35 | X | 0.51 |
| Daisuke Matsuzaka | 35.0 | 8.23 | 8 | 0 | X | -3.19 |
| Junichi Tazawa | 17.7 | 3.57 | 3 | 1 | X | 0.31 |
| Javier Lopez | 11.7 | 9.26 | 0 | 14 | X | -1.34 |
| Hunter Jones | 9.0 | 8.00 | 0 | 8 | X | -0.77 |
| Michael Bowden | 4.0 | 15.75 | 0 | 2 | X | -1.07 |
| Fernando Cabrera | 4.0 | 4.50 | 0 | 4 | X | -0.02 |
| Enrique Gonzalez | 3.7 | 4.91 | 0 | 2 | X | -0.05 |
| Billy Traber | 3.7 | 14.73 | 0 | 1 | X | -0.89 |
| Jonathan Van Every | 0.7 | 0.00 | 0 | 1 | X | 0.07 |
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