| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 542 | 91 | 55 | 0.299 | 0.373 | 2.20 | 2B |
| Jacoby Ellsbury | 526 | 66 | 44 | 0.292 | 0.337 | -1.19 | CF |
| Jason Bay | 500 | 79 | 89 | 0.257 | 0.382 | 5.53 | LF |
| David Ortiz | 480 | 56 | 76 | 0.229 | 0.323 | 2.24 | DH |
| Kevin Youkilis | 448 | 77 | 72 | 0.307 | 0.420 | 4.80 | 1B-3B |
| J.D. Drew | 428 | 65 | 48 | 0.259 | 0.374 | 1.50 | RF |
| Mike Lowell | 388 | 47 | 62 | 0.304 | 0.348 | 2.05 | 3B |
| Jason Varitek | 365 | 38 | 48 | 0.223 | 0.332 | 0.19 | CR |
| Nick Green | 301 | 33 | 35 | 0.230 | 0.296 | -0.15 | SS |
| Rocco Baldelli | 129 | 18 | 20 | 0.267 | 0.333 | 0.87 | RF |
| Julio Lugo | 123 | 16 | 8 | 0.284 | 0.350 | -0.46 | 2B-SS |
| George Kottaras | 99 | 14 | 9 | 0.224 | 0.303 | 0.02 | CR |
| Victor Martinez | 94 | 12 | 16 | 0.337 | 0.404 | 0.66 | CR-1B |
| Jeff Bailey | 91 | 14 | 10 | 0.208 | 0.330 | 0.32 | 1B |
| Mark Kotsay | 79 | 5 | 5 | 0.257 | 0.291 | -0.86 | 1B |
| Jed Lowrie | 63 | 2 | 7 | 0.143 | 0.206 | -0.58 | SS |
| Casey Kotchman | 36 | 6 | 4 | 0.250 | 0.333 | 0.18 | 1B |
| Josh Reddick | 33 | 2 | 2 | 0.188 | 0.212 | -0.38 | LF-RF |
| Alex Gonzalez | 32 | 3 | 4 | 0.188 | 0.188 | -0.04 | SS |
| Adam LaRoche | 19 | 2 | 3 | 0.263 | 0.263 | 0.06 | 1B |
| Jonathan Van Every | 13 | 1 | 3 | 0.364 | 0.462 | 0.11 | X |
| Aaron Bates | 12 | 1 | 2 | 0.364 | 0.417 | 0.02 | X |
| Brian Anderson | 7 | 0 | 1 | 0.167 | 0.143 | -0.06 | CF |
| Chris Woodward | 7 | 0 | 0 | 0.000 | 0.429 | -0.17 | 3B |
| Chris Carter | 6 | 0 | 1 | 0.000 | 0.000 | -0.04 | X |
| Gil Velazquez | 3 | 0 | 0 | 0.000 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Josh Beckett | 170.3 | 3.65 | 25 | 0 | X | 2.68 |
| Jon Lester | 161.0 | 3.58 | 25 | 0 | X | 2.79 |
| Brad Penny | 131.7 | 5.61 | 24 | 0 | X | -3.95 |
| Tim Wakefield | 108.7 | 4.31 | 17 | 0 | X | 0.03 |
| Justin Masterson | 72.0 | 4.25 | 6 | 25 | X | 0.12 |
| Ramon Ramirez | 54.0 | 2.67 | 0 | 54 | X | 2.08 |
| Hideki Okajima | 52.0 | 2.77 | 0 | 55 | X | 1.88 |
| Jonathan Papelbon | 52.0 | 2.08 | 0 | 51 | X | 2.72 |
| Manny Delcarmen | 49.3 | 3.83 | 0 | 51 | X | 0.56 |
| Takashi Saito | 45.0 | 2.80 | 0 | 45 | X | 1.60 |
| John Smoltz | 40.0 | 8.10 | 8 | 0 | X | -3.53 |
| Clay Buchholz | 38.3 | 3.99 | 7 | 0 | X | 0.29 |
| Daniel Bard | 37.0 | 3.65 | 0 | 34 | X | 0.58 |
| Daisuke Matsuzaka | 35.0 | 8.23 | 8 | 0 | X | -3.19 |
| Junichi Tazawa | 17.7 | 3.57 | 3 | 1 | X | 0.31 |
| Javier Lopez | 11.7 | 9.26 | 0 | 14 | X | -1.34 |
| Hunter Jones | 9.0 | 8.00 | 0 | 8 | X | -0.77 |
| Michael Bowden | 4.0 | 15.75 | 0 | 2 | X | -1.07 |
| Fernando Cabrera | 4.0 | 4.50 | 0 | 4 | X | -0.02 |
| Enrique Gonzalez | 3.7 | 4.91 | 0 | 2 | X | -0.05 |
| Billy Traber | 3.7 | 14.73 | 0 | 1 | X | -0.89 |
| Jonathan Van Every | 0.7 | 0.00 | 0 | 1 | X | 0.07 |
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