| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 523 | 86 | 53 | 0.295 | 0.369 | 1.87 | 2B |
| Jacoby Ellsbury | 496 | 64 | 38 | 0.295 | 0.341 | -1.35 | CF |
| Jason Bay | 475 | 73 | 85 | 0.259 | 0.385 | 5.04 | LF |
| David Ortiz | 456 | 48 | 66 | 0.220 | 0.314 | 0.88 | DH |
| Kevin Youkilis | 422 | 71 | 66 | 0.311 | 0.424 | 4.12 | 1B-3B |
| J.D. Drew | 408 | 62 | 44 | 0.254 | 0.373 | 1.21 | RF |
| Mike Lowell | 370 | 42 | 59 | 0.299 | 0.346 | 1.61 | 3B |
| Jason Varitek | 355 | 37 | 46 | 0.223 | 0.332 | 0.08 | CR |
| Nick Green | 289 | 29 | 35 | 0.233 | 0.298 | -0.31 | SS |
| Julio Lugo | 123 | 16 | 8 | 0.284 | 0.350 | -0.47 | 2B-SS |
| Rocco Baldelli | 121 | 16 | 17 | 0.261 | 0.322 | 0.52 | RF |
| George Kottaras | 99 | 14 | 9 | 0.224 | 0.303 | 0.01 | CR |
| Jeff Bailey | 91 | 14 | 10 | 0.208 | 0.330 | 0.31 | 1B |
| Mark Kotsay | 79 | 5 | 5 | 0.257 | 0.291 | -0.87 | 1B |
| Victor Martinez | 68 | 7 | 11 | 0.311 | 0.382 | 0.24 | CR-1B |
| Jed Lowrie | 63 | 2 | 7 | 0.143 | 0.206 | -0.59 | SS |
| Josh Reddick | 33 | 2 | 2 | 0.188 | 0.212 | -0.38 | LF-RF |
| Casey Kotchman | 27 | 3 | 3 | 0.208 | 0.296 | -0.03 | 1B |
| Adam LaRoche | 19 | 2 | 3 | 0.263 | 0.263 | 0.06 | 1B |
| Jonathan Van Every | 13 | 1 | 3 | 0.364 | 0.462 | 0.10 | X |
| Aaron Bates | 12 | 1 | 2 | 0.364 | 0.417 | 0.02 | X |
| Alex Gonzalez | 8 | 0 | 0 | 0.125 | 0.125 | -0.19 | SS |
| Brian Anderson | 7 | 0 | 1 | 0.167 | 0.143 | -0.07 | CF |
| Chris Woodward | 7 | 0 | 0 | 0.000 | 0.429 | -0.17 | 3B |
| Chris Carter | 6 | 0 | 1 | 0.000 | 0.000 | -0.04 | X |
| Gil Velazquez | 3 | 0 | 0 | 0.000 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Josh Beckett | 157.0 | 3.10 | 23 | 0 | X | 4.50 |
| Jon Lester | 153.0 | 3.71 | 24 | 0 | X | 2.21 |
| Brad Penny | 127.7 | 5.22 | 23 | 0 | X | -2.66 |
| Tim Wakefield | 108.7 | 4.31 | 17 | 0 | X | 0.04 |
| Justin Masterson | 72.0 | 4.25 | 6 | 25 | X | 0.13 |
| Ramon Ramirez | 52.0 | 2.25 | 0 | 52 | X | 2.52 |
| Jonathan Papelbon | 50.7 | 2.13 | 0 | 50 | X | 2.59 |
| Hideki Okajima | 50.0 | 2.88 | 0 | 53 | X | 1.69 |
| Manny Delcarmen | 47.7 | 3.78 | 0 | 49 | X | 0.61 |
| Takashi Saito | 42.0 | 3.00 | 0 | 42 | X | 1.30 |
| John Smoltz | 40.0 | 8.10 | 8 | 0 | X | -3.52 |
| Daniel Bard | 35.3 | 3.06 | 0 | 32 | X | 1.05 |
| Daisuke Matsuzaka | 35.0 | 8.23 | 8 | 0 | X | -3.19 |
| Clay Buchholz | 32.3 | 4.45 | 6 | 0 | X | -0.10 |
| Junichi Tazawa | 11.7 | 5.40 | 2 | 1 | X | -0.29 |
| Javier Lopez | 11.7 | 9.26 | 0 | 14 | X | -1.34 |
| Hunter Jones | 9.0 | 8.00 | 0 | 8 | X | -0.77 |
| Billy Traber | 3.7 | 14.73 | 0 | 1 | X | -0.89 |
| Fernando Cabrera | 3.0 | 6.00 | 0 | 3 | X | -0.12 |
| Michael Bowden | 2.0 | 0.00 | 0 | 1 | X | 0.20 |
| Enrique Gonzalez | 1.7 | 10.80 | 0 | 1 | X | -0.25 |
| Jonathan Van Every | 0.7 | 0.00 | 0 | 1 | X | 0.07 |
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