| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Michael Young | 474 | 63 | 53 | 0.323 | 0.378 | 0.26 | 3B |
| Ian Kinsler | 445 | 71 | 64 | 0.242 | 0.312 | 2.98 | 2B |
| Marlon Byrd | 408 | 45 | 56 | 0.285 | 0.324 | 0.34 | CF-LF |
| Nelson Cruz | 380 | 56 | 57 | 0.269 | 0.337 | 2.31 | RF |
| Hank Blalock | 375 | 51 | 56 | 0.246 | 0.283 | 1.80 | 1B-DH |
| Elvis Andrus | 342 | 43 | 19 | 0.262 | 0.319 | -2.09 | SS |
| David Murphy | 303 | 34 | 32 | 0.271 | 0.347 | -0.69 | LF-DH-RF |
| Jarrod Saltalamacchia | 298 | 34 | 35 | 0.241 | 0.292 | -0.25 | CR |
| Chris Davis | 277 | 31 | 35 | 0.202 | 0.256 | -0.04 | 1B-3B |
| Andruw Jones | 270 | 41 | 38 | 0.224 | 0.337 | 1.50 | DH-LF |
| Josh Hamilton | 258 | 30 | 33 | 0.235 | 0.291 | 0.13 | CF-RF |
| Omar Vizquel | 135 | 15 | 11 | 0.287 | 0.326 | -0.67 | SS-3B-2B |
| Taylor Teagarden | 126 | 12 | 19 | 0.204 | 0.262 | 0.09 | CR |
| Brandon Boggs | 18 | 0 | 0 | 0.059 | 0.111 | -0.45 | X |
| Julio Borbon | 10 | 2 | 1 | 0.200 | 0.200 | 0.06 | DH-LF |
| Joaquin Arias | 9 | 0 | 0 | 0.000 | 0.000 | -0.23 | X |
| Esteban German | 9 | 3 | 0 | 0.286 | 0.444 | 0.09 | 3B |
| Greg Golson | 1 | 0 | 0 | 0.000 | 0.000 | -0.03 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Kevin Millwood | 144.0 | 3.38 | 22 | 0 | X | 3.18 |
| Scott Feldman | 125.7 | 3.94 | 20 | 3 | X | 1.12 |
| Vicente Padilla | 108.0 | 4.92 | 18 | 0 | X | -1.50 |
| Derek Holland | 91.0 | 5.04 | 12 | 12 | X | -1.53 |
| Brandon McCarthy | 64.0 | 4.92 | 11 | 0 | X | -0.90 |
| Matt Harrison | 63.3 | 6.11 | 11 | 0 | X | -2.64 |
| Jason Jennings | 56.7 | 3.81 | 0 | 39 | X | 0.67 |
| C.J. Wilson | 49.3 | 3.28 | 0 | 49 | X | 1.19 |
| Tommy Hunter | 48.0 | 2.62 | 8 | 0 | X | 1.90 |
| Darren O'Day | 38.3 | 1.88 | 0 | 43 | X | 2.18 |
| Eddie Guardado | 33.0 | 4.09 | 0 | 41 | X | 0.18 |
| Frank Francisco | 30.3 | 2.08 | 0 | 31 | X | 1.59 |
| Doug Mathis | 27.0 | 3.00 | 2 | 11 | X | 0.83 |
| Dustin Nippert | 26.3 | 2.73 | 4 | 4 | X | 0.98 |
| Kris Benson | 22.3 | 8.46 | 2 | 6 | X | -2.16 |
| Jason Grilli | 17.7 | 1.53 | 0 | 17 | X | 1.15 |
| Warner Madrigal | 9.7 | 9.31 | 0 | 10 | X | -1.13 |
| Guillermo Moscoso | 8.3 | 4.32 | 0 | 5 | X | 0.00 |
| Willie Eyre | 7.3 | 4.91 | 0 | 6 | X | -0.10 |
| Josh Rupe | 4.7 | 15.43 | 0 | 4 | X | -1.21 |
| Neftali Feliz | 4.7 | 1.93 | 0 | 3 | X | 0.26 |
| Luis Mendoza | 1.0 | 36.00 | 0 | 1 | X | -0.74 |
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