| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 487 | 80 | 50 | 0.303 | 0.376 | 1.90 | 2B |
| Jacoby Ellsbury | 459 | 60 | 37 | 0.298 | 0.346 | -0.89 | CF |
| Jason Bay | 441 | 67 | 77 | 0.252 | 0.381 | 4.48 | LF |
| David Ortiz | 421 | 42 | 62 | 0.220 | 0.306 | 0.76 | DH |
| Kevin Youkilis | 408 | 70 | 66 | 0.310 | 0.424 | 4.44 | 1B-3B |
| J.D. Drew | 384 | 59 | 42 | 0.246 | 0.367 | 1.34 | RF |
| Mike Lowell | 339 | 37 | 54 | 0.298 | 0.339 | 1.38 | 3B |
| Jason Varitek | 336 | 37 | 45 | 0.225 | 0.333 | 0.50 | CR |
| Nick Green | 267 | 28 | 33 | 0.235 | 0.303 | -0.04 | SS |
| Julio Lugo | 123 | 16 | 8 | 0.284 | 0.350 | -0.45 | 2B-SS |
| Rocco Baldelli | 121 | 16 | 17 | 0.261 | 0.322 | 0.55 | RF |
| George Kottaras | 99 | 14 | 9 | 0.224 | 0.303 | 0.03 | CR |
| Jeff Bailey | 91 | 14 | 10 | 0.208 | 0.330 | 0.32 | 1B |
| Mark Kotsay | 79 | 5 | 5 | 0.257 | 0.291 | -0.86 | 1B |
| Jed Lowrie | 63 | 2 | 7 | 0.143 | 0.206 | -0.57 | SS |
| Victor Martinez | 33 | 4 | 6 | 0.333 | 0.394 | 0.25 | CR-1B |
| Josh Reddick | 24 | 2 | 2 | 0.217 | 0.250 | -0.16 | LF-RF |
| Adam LaRoche | 19 | 2 | 3 | 0.263 | 0.263 | 0.07 | 1B |
| Jonathan Van Every | 13 | 1 | 3 | 0.364 | 0.462 | 0.11 | X |
| Aaron Bates | 12 | 1 | 2 | 0.364 | 0.417 | 0.03 | X |
| Casey Kotchman | 7 | 2 | 2 | 0.167 | 0.286 | 0.25 | 1B |
| Chris Carter | 6 | 0 | 1 | 0.000 | 0.000 | -0.04 | X |
| Gil Velazquez | 3 | 0 | 0 | 0.000 | 0.333 | -0.07 | X |
| Chris Woodward | 3 | 0 | 0 | 0.000 | 0.333 | -0.07 | 3B |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Josh Beckett | 150.0 | 3.12 | 22 | 0 | X | 4.09 |
| Jon Lester | 140.0 | 3.79 | 22 | 0 | X | 1.62 |
| Brad Penny | 116.0 | 5.20 | 21 | 0 | X | -2.46 |
| Tim Wakefield | 108.7 | 4.31 | 17 | 0 | X | -0.05 |
| Justin Masterson | 72.0 | 4.25 | 6 | 25 | X | 0.06 |
| Ramon Ramirez | 48.0 | 2.25 | 0 | 47 | X | 2.28 |
| Jonathan Papelbon | 47.3 | 1.90 | 0 | 47 | X | 2.64 |
| Hideki Okajima | 46.7 | 2.89 | 0 | 50 | X | 1.52 |
| Manny Delcarmen | 45.3 | 3.38 | 0 | 46 | X | 0.97 |
| John Smoltz | 40.0 | 8.10 | 8 | 0 | X | -3.56 |
| Takashi Saito | 40.0 | 3.15 | 0 | 40 | X | 1.06 |
| Daisuke Matsuzaka | 35.0 | 8.23 | 8 | 0 | X | -3.22 |
| Daniel Bard | 32.7 | 2.20 | 0 | 29 | X | 1.59 |
| Clay Buchholz | 19.3 | 6.05 | 4 | 0 | X | -0.80 |
| Javier Lopez | 11.7 | 9.26 | 0 | 14 | X | -1.35 |
| Hunter Jones | 9.0 | 8.00 | 0 | 8 | X | -0.78 |
| Billy Traber | 3.7 | 14.73 | 0 | 1 | X | -0.89 |
| Michael Bowden | 2.0 | 0.00 | 0 | 1 | X | 0.20 |
| Junichi Tazawa | 1.7 | 10.80 | 0 | 1 | X | -0.25 |
| Jonathan Van Every | 0.7 | 0.00 | 0 | 1 | X | 0.07 |
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