| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 356 | 57 | 37 | 0.288 | 0.368 | 1.32 | 2B |
| Jason Bay | 340 | 51 | 71 | 0.262 | 0.371 | 4.64 | LF |
| Jacoby Ellsbury | 331 | 41 | 26 | 0.302 | 0.347 | -0.91 | CF |
| David Ortiz | 306 | 30 | 36 | 0.221 | 0.317 | -0.42 | DH |
| J.D. Drew | 283 | 44 | 35 | 0.267 | 0.385 | 1.50 | RF |
| Kevin Youkilis | 283 | 49 | 47 | 0.307 | 0.431 | 3.28 | 1B-3B |
| Mike Lowell | 282 | 30 | 41 | 0.282 | 0.319 | 0.68 | 3B |
| Jason Varitek | 241 | 31 | 33 | 0.234 | 0.336 | 0.93 | CR |
| Nick Green | 202 | 24 | 28 | 0.272 | 0.332 | 0.61 | SS |
| Julio Lugo | 116 | 16 | 8 | 0.301 | 0.362 | -0.27 | 2B-SS |
| Jeff Bailey | 88 | 14 | 10 | 0.216 | 0.341 | 0.41 | 1B |
| Rocco Baldelli | 83 | 12 | 13 | 0.289 | 0.349 | 0.63 | RF |
| George Kottaras | 83 | 12 | 9 | 0.233 | 0.289 | 0.21 | CR |
| Mark Kotsay | 52 | 4 | 2 | 0.300 | 0.327 | -0.62 | 1B |
| Jed Lowrie | 20 | 0 | 0 | 0.056 | 0.150 | -0.48 | SS |
| Jonathan Van Every | 13 | 1 | 3 | 0.364 | 0.462 | 0.11 | X |
| Chris Carter | 6 | 0 | 1 | 0.000 | 0.000 | -0.04 | X |
| Gil Velazquez | 3 | 0 | 0 | 0.000 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Josh Beckett | 105.3 | 3.67 | 16 | 0 | X | 1.50 |
| Tim Wakefield | 102.7 | 4.30 | 16 | 0 | X | -0.03 |
| Jon Lester | 99.3 | 4.35 | 16 | 0 | X | -0.15 |
| Brad Penny | 82.7 | 4.79 | 15 | 0 | X | -0.98 |
| Justin Masterson | 61.0 | 4.13 | 6 | 16 | X | 0.22 |
| Ramon Ramirez | 36.0 | 2.25 | 0 | 36 | X | 1.71 |
| Jonathan Papelbon | 36.0 | 1.75 | 0 | 36 | X | 2.13 |
| Daisuke Matsuzaka | 35.0 | 8.23 | 8 | 0 | X | -3.22 |
| Hideki Okajima | 34.0 | 3.44 | 0 | 36 | X | 0.67 |
| Manny Delcarmen | 32.0 | 2.25 | 0 | 32 | X | 1.52 |
| Takashi Saito | 27.7 | 3.25 | 0 | 29 | X | 0.67 |
| Daniel Bard | 20.3 | 3.10 | 0 | 17 | X | 0.56 |
| Javier Lopez | 11.7 | 9.26 | 0 | 14 | X | -1.35 |
| John Smoltz | 9.0 | 6.00 | 2 | 0 | X | -0.36 |
| Hunter Jones | 9.0 | 8.00 | 0 | 8 | X | -0.78 |
| Michael Bowden | 2.0 | 0.00 | 0 | 1 | X | 0.20 |
| Jonathan Van Every | 0.7 | 0.00 | 0 | 1 | X | 0.07 |
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