| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 321 | 52 | 31 | 0.289 | 0.371 | 0.91 | 2B |
| Jason Bay | 311 | 49 | 70 | 0.282 | 0.392 | 4.93 | LF |
| Jacoby Ellsbury | 303 | 37 | 24 | 0.306 | 0.353 | -0.97 | CF |
| Mike Lowell | 281 | 30 | 41 | 0.283 | 0.320 | 0.62 | 3B |
| David Ortiz | 275 | 28 | 34 | 0.215 | 0.309 | -0.18 | DH |
| J.D. Drew | 254 | 40 | 31 | 0.260 | 0.390 | 1.28 | RF |
| Kevin Youkilis | 250 | 44 | 42 | 0.312 | 0.440 | 2.95 | 1B-3B |
| Jason Varitek | 221 | 30 | 30 | 0.232 | 0.326 | 0.92 | CR |
| Nick Green | 184 | 23 | 26 | 0.284 | 0.337 | 0.67 | SS |
| Julio Lugo | 104 | 14 | 7 | 0.304 | 0.375 | -0.32 | 2B-SS |
| Jeff Bailey | 81 | 10 | 10 | 0.188 | 0.309 | 0.13 | 1B |
| Rocco Baldelli | 77 | 12 | 11 | 0.286 | 0.351 | 0.54 | RF |
| George Kottaras | 72 | 11 | 8 | 0.242 | 0.306 | 0.24 | CR |
| Mark Kotsay | 31 | 3 | 1 | 0.267 | 0.290 | -0.33 | 1B |
| Jed Lowrie | 20 | 0 | 0 | 0.056 | 0.150 | -0.49 | SS |
| Jonathan Van Every | 13 | 1 | 3 | 0.364 | 0.462 | 0.10 | X |
| Chris Carter | 6 | 0 | 1 | 0.000 | 0.000 | -0.04 | X |
| Gil Velazquez | 3 | 0 | 0 | 0.000 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 92.3 | 4.68 | 15 | 0 | X | -0.72 |
| Josh Beckett | 91.3 | 3.74 | 14 | 0 | X | 1.28 |
| Tim Wakefield | 88.7 | 4.47 | 14 | 0 | X | -0.25 |
| Brad Penny | 76.7 | 4.93 | 14 | 0 | X | -1.05 |
| Justin Masterson | 58.3 | 3.70 | 6 | 14 | X | 0.87 |
| Daisuke Matsuzaka | 35.0 | 8.23 | 8 | 0 | X | -3.17 |
| Ramon Ramirez | 33.3 | 1.89 | 0 | 33 | X | 1.91 |
| Hideki Okajima | 32.3 | 2.51 | 0 | 33 | X | 1.39 |
| Jonathan Papelbon | 31.0 | 1.74 | 0 | 30 | X | 1.88 |
| Manny Delcarmen | 28.3 | 2.22 | 0 | 28 | X | 1.40 |
| Takashi Saito | 26.3 | 3.08 | 0 | 27 | X | 0.78 |
| Daniel Bard | 17.3 | 3.63 | 0 | 15 | X | 0.29 |
| Javier Lopez | 11.7 | 9.26 | 0 | 14 | X | -1.34 |
| Hunter Jones | 9.0 | 8.00 | 0 | 8 | X | -0.77 |
| John Smoltz | 5.0 | 9.00 | 1 | 0 | X | -0.54 |
| Michael Bowden | 2.0 | 0.00 | 0 | 1 | X | 0.20 |
| Jonathan Van Every | 0.7 | 0.00 | 0 | 1 | X | 0.07 |
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