| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 307 | 49 | 30 | 0.286 | 0.371 | 0.83 | 2B |
| Jason Bay | 298 | 46 | 67 | 0.276 | 0.393 | 4.62 | LF |
| Jacoby Ellsbury | 291 | 36 | 21 | 0.300 | 0.347 | -1.09 | CF |
| Mike Lowell | 272 | 30 | 41 | 0.288 | 0.324 | 0.84 | 3B |
| David Ortiz | 268 | 26 | 30 | 0.212 | 0.310 | -0.63 | DH |
| J.D. Drew | 241 | 38 | 31 | 0.258 | 0.386 | 1.39 | RF |
| Kevin Youkilis | 239 | 41 | 40 | 0.316 | 0.444 | 2.70 | 1B-3B |
| Jason Varitek | 209 | 28 | 26 | 0.228 | 0.325 | 0.59 | CR |
| Nick Green | 171 | 22 | 25 | 0.293 | 0.345 | 0.78 | SS |
| Julio Lugo | 102 | 13 | 7 | 0.300 | 0.373 | -0.38 | 2B-SS |
| Jeff Bailey | 81 | 10 | 10 | 0.188 | 0.309 | 0.13 | 1B |
| Rocco Baldelli | 73 | 10 | 9 | 0.273 | 0.342 | 0.22 | RF |
| George Kottaras | 71 | 11 | 8 | 0.246 | 0.310 | 0.27 | CR |
| Mark Kotsay | 28 | 3 | 1 | 0.259 | 0.286 | -0.26 | 1B |
| Jed Lowrie | 20 | 0 | 0 | 0.056 | 0.150 | -0.49 | SS |
| Jonathan Van Every | 13 | 1 | 3 | 0.364 | 0.462 | 0.10 | X |
| Chris Carter | 6 | 0 | 1 | 0.000 | 0.000 | -0.04 | X |
| Gil Velazquez | 3 | 0 | 0 | 0.000 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Josh Beckett | 91.3 | 3.74 | 14 | 0 | X | 1.26 |
| Tim Wakefield | 88.7 | 4.47 | 14 | 0 | X | -0.27 |
| Jon Lester | 86.3 | 4.69 | 14 | 0 | X | -0.71 |
| Brad Penny | 71.0 | 4.94 | 13 | 0 | X | -1.00 |
| Justin Masterson | 56.7 | 3.65 | 6 | 13 | X | 0.91 |
| Daisuke Matsuzaka | 35.0 | 8.23 | 8 | 0 | X | -3.18 |
| Ramon Ramirez | 32.3 | 1.95 | 0 | 32 | X | 1.80 |
| Hideki Okajima | 31.0 | 2.61 | 0 | 31 | X | 1.25 |
| Jonathan Papelbon | 30.0 | 1.80 | 0 | 29 | X | 1.78 |
| Manny Delcarmen | 28.0 | 2.25 | 0 | 27 | X | 1.36 |
| Takashi Saito | 24.3 | 2.59 | 0 | 25 | X | 0.99 |
| Daniel Bard | 15.3 | 2.93 | 0 | 13 | X | 0.50 |
| Javier Lopez | 11.7 | 9.26 | 0 | 14 | X | -1.34 |
| Hunter Jones | 9.0 | 8.00 | 0 | 8 | X | -0.77 |
| Michael Bowden | 2.0 | 0.00 | 0 | 1 | X | 0.20 |
| Jonathan Van Every | 0.7 | 0.00 | 0 | 1 | X | 0.07 |
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