| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Jacoby Ellsbury | 229 | 28 | 15 | 0.298 | 0.332 | -1.16 | CF |
| Dustin Pedroia | 227 | 39 | 21 | 0.326 | 0.414 | 0.68 | 2B |
| Jason Bay | 217 | 38 | 49 | 0.288 | 0.415 | 3.76 | LF |
| David Ortiz | 208 | 16 | 18 | 0.184 | 0.284 | -1.58 | DH |
| Mike Lowell | 205 | 25 | 35 | 0.308 | 0.332 | 1.22 | 3B |
| J.D. Drew | 181 | 28 | 22 | 0.248 | 0.359 | 0.77 | RF |
| Kevin Youkilis | 161 | 31 | 31 | 0.366 | 0.478 | 2.52 | 1B-3B |
| Jason Varitek | 159 | 19 | 22 | 0.239 | 0.327 | 0.37 | CR |
| Nick Green | 114 | 12 | 15 | 0.298 | 0.360 | 0.01 | SS |
| Julio Lugo | 84 | 9 | 4 | 0.276 | 0.345 | -0.72 | 2B-SS |
| Jeff Bailey | 81 | 10 | 10 | 0.188 | 0.309 | 0.09 | 1B |
| George Kottaras | 51 | 6 | 5 | 0.205 | 0.275 | -0.11 | CR |
| Rocco Baldelli | 47 | 5 | 6 | 0.244 | 0.277 | -0.01 | RF |
| Jed Lowrie | 20 | 0 | 0 | 0.056 | 0.150 | -0.50 | SS |
| Jonathan Van Every | 13 | 1 | 3 | 0.364 | 0.462 | 0.10 | X |
| Chris Carter | 6 | 0 | 1 | 0.000 | 0.000 | -0.04 | X |
| Gil Velazquez | 3 | 0 | 0 | 0.000 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 65.3 | 5.65 | 11 | 0 | X | -1.82 |
| Tim Wakefield | 63.3 | 4.55 | 10 | 0 | X | -0.14 |
| Josh Beckett | 62.7 | 4.60 | 10 | 0 | X | -0.21 |
| Brad Penny | 54.3 | 5.63 | 10 | 0 | X | -1.50 |
| Justin Masterson | 48.7 | 4.25 | 6 | 7 | X | 0.22 |
| Ramon Ramirez | 26.0 | 1.38 | 0 | 24 | X | 1.86 |
| Hideki Okajima | 22.0 | 2.45 | 0 | 23 | X | 1.02 |
| Jonathan Papelbon | 22.0 | 2.45 | 0 | 21 | X | 1.02 |
| Manny Delcarmen | 22.0 | 1.23 | 0 | 21 | X | 1.65 |
| Takashi Saito | 18.0 | 3.00 | 0 | 18 | X | 0.61 |
| Daisuke Matsuzaka | 16.3 | 8.82 | 4 | 0 | X | -1.66 |
| Javier Lopez | 11.7 | 9.26 | 0 | 14 | X | -1.31 |
| Hunter Jones | 9.0 | 8.00 | 0 | 8 | X | -0.75 |
| Daniel Bard | 8.3 | 1.08 | 0 | 6 | X | 0.66 |
| Michael Bowden | 2.0 | 0.00 | 0 | 1 | X | 0.21 |
| Jonathan Van Every | 0.7 | 0.00 | 0 | 1 | X | 0.07 |
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