| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Jacoby Ellsbury | 220 | 28 | 15 | 0.303 | 0.336 | -0.94 | CF |
| Dustin Pedroia | 218 | 37 | 18 | 0.330 | 0.413 | 0.37 | 2B |
| Jason Bay | 208 | 37 | 48 | 0.287 | 0.409 | 3.77 | LF |
| David Ortiz | 199 | 15 | 18 | 0.188 | 0.291 | -1.47 | DH |
| Mike Lowell | 196 | 25 | 33 | 0.302 | 0.327 | 1.23 | 3B |
| J.D. Drew | 174 | 28 | 21 | 0.252 | 0.368 | 0.83 | RF |
| Kevin Youkilis | 152 | 28 | 29 | 0.374 | 0.487 | 2.21 | 1B-3B |
| Jason Varitek | 150 | 17 | 22 | 0.248 | 0.320 | 0.37 | CR |
| Nick Green | 106 | 11 | 15 | 0.299 | 0.358 | 0.10 | SS |
| Julio Lugo | 84 | 9 | 4 | 0.276 | 0.345 | -0.72 | 2B-SS |
| Jeff Bailey | 81 | 10 | 10 | 0.188 | 0.309 | 0.09 | 1B |
| George Kottaras | 51 | 6 | 5 | 0.205 | 0.275 | -0.11 | CR |
| Rocco Baldelli | 45 | 4 | 4 | 0.233 | 0.267 | -0.28 | RF |
| Jed Lowrie | 20 | 0 | 0 | 0.056 | 0.150 | -0.50 | SS |
| Jonathan Van Every | 13 | 1 | 3 | 0.364 | 0.462 | 0.10 | X |
| Chris Carter | 6 | 0 | 1 | 0.000 | 0.000 | -0.04 | X |
| Gil Velazquez | 3 | 0 | 0 | 0.000 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Tim Wakefield | 63.3 | 4.55 | 10 | 0 | X | -0.15 |
| Josh Beckett | 62.7 | 4.60 | 10 | 0 | X | -0.22 |
| Jon Lester | 59.3 | 6.07 | 10 | 0 | X | -2.25 |
| Brad Penny | 48.3 | 5.96 | 9 | 0 | X | -1.71 |
| Justin Masterson | 46.7 | 4.24 | 6 | 6 | X | 0.22 |
| Ramon Ramirez | 24.3 | 0.74 | 0 | 22 | X | 2.10 |
| Jonathan Papelbon | 22.0 | 2.45 | 0 | 21 | X | 1.02 |
| Manny Delcarmen | 21.7 | 1.25 | 0 | 20 | X | 1.62 |
| Hideki Okajima | 21.0 | 2.57 | 0 | 22 | X | 0.92 |
| Takashi Saito | 18.0 | 3.00 | 0 | 18 | X | 0.61 |
| Daisuke Matsuzaka | 16.3 | 8.82 | 4 | 0 | X | -1.67 |
| Javier Lopez | 11.7 | 9.26 | 0 | 14 | X | -1.31 |
| Hunter Jones | 9.0 | 8.00 | 0 | 8 | X | -0.75 |
| Daniel Bard | 8.3 | 1.08 | 0 | 6 | X | 0.65 |
| Michael Bowden | 2.0 | 0.00 | 0 | 1 | X | 0.21 |
| Jonathan Van Every | 0.7 | 0.00 | 0 | 1 | X | 0.07 |
_