| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Jacoby Ellsbury | 202 | 25 | 13 | 0.298 | 0.332 | -1.05 | CF |
| Dustin Pedroia | 201 | 37 | 16 | 0.337 | 0.428 | 0.55 | 2B |
| Jason Bay | 196 | 36 | 47 | 0.289 | 0.418 | 3.83 | LF |
| Mike Lowell | 184 | 24 | 33 | 0.305 | 0.332 | 1.40 | 3B |
| David Ortiz | 183 | 15 | 18 | 0.194 | 0.301 | -1.10 | DH |
| J.D. Drew | 158 | 27 | 20 | 0.269 | 0.380 | 1.00 | RF |
| Jason Varitek | 143 | 15 | 20 | 0.238 | 0.315 | 0.11 | CR |
| Kevin Youkilis | 136 | 28 | 28 | 0.384 | 0.493 | 2.49 | 1B-3B |
| Nick Green | 103 | 11 | 15 | 0.309 | 0.369 | 0.16 | SS |
| Jeff Bailey | 73 | 9 | 10 | 0.197 | 0.329 | 0.17 | 1B |
| Julio Lugo | 72 | 9 | 4 | 0.258 | 0.319 | -0.43 | 2B-SS |
| Rocco Baldelli | 45 | 4 | 4 | 0.233 | 0.267 | -0.28 | RF |
| George Kottaras | 42 | 5 | 5 | 0.200 | 0.286 | 0.00 | CR |
| Jed Lowrie | 20 | 0 | 0 | 0.056 | 0.150 | -0.50 | SS |
| Jonathan Van Every | 13 | 1 | 3 | 0.364 | 0.462 | 0.10 | X |
| Chris Carter | 6 | 0 | 1 | 0.000 | 0.000 | -0.04 | X |
| Gil Velazquez | 3 | 0 | 0 | 0.000 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Tim Wakefield | 58.7 | 3.99 | 9 | 0 | X | 0.66 |
| Josh Beckett | 55.7 | 5.01 | 9 | 0 | X | -0.71 |
| Jon Lester | 53.3 | 5.91 | 9 | 0 | X | -1.79 |
| Brad Penny | 48.3 | 5.96 | 9 | 0 | X | -1.68 |
| Justin Masterson | 44.3 | 4.47 | 6 | 5 | X | 0.00 |
| Ramon Ramirez | 24.3 | 0.74 | 0 | 22 | X | 2.12 |
| Manny Delcarmen | 21.0 | 0.86 | 0 | 19 | X | 1.77 |
| Jonathan Papelbon | 21.0 | 2.57 | 0 | 20 | X | 0.93 |
| Hideki Okajima | 20.0 | 2.70 | 0 | 21 | X | 0.83 |
| Takashi Saito | 16.0 | 3.38 | 0 | 16 | X | 0.41 |
| Javier Lopez | 11.7 | 9.26 | 0 | 14 | X | -1.30 |
| Daisuke Matsuzaka | 11.3 | 10.32 | 3 | 0 | X | -1.55 |
| Hunter Jones | 9.0 | 8.00 | 0 | 8 | X | -0.74 |
| Daniel Bard | 5.0 | 1.80 | 0 | 4 | X | 0.31 |
| Michael Bowden | 2.0 | 0.00 | 0 | 1 | X | 0.21 |
| Jonathan Van Every | 0.7 | 0.00 | 0 | 1 | X | 0.07 |
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