| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 179 | 31 | 14 | 0.314 | 0.408 | 0.25 | 2B |
| Jacoby Ellsbury | 179 | 20 | 13 | 0.302 | 0.335 | -1.01 | CF |
| Jason Bay | 174 | 33 | 42 | 0.302 | 0.437 | 3.53 | LF |
| David Ortiz | 166 | 15 | 17 | 0.209 | 0.319 | -0.79 | DH |
| Mike Lowell | 163 | 21 | 29 | 0.295 | 0.325 | 1.18 | 3B |
| J.D. Drew | 141 | 24 | 19 | 0.256 | 0.383 | 0.99 | RF |
| Jason Varitek | 128 | 14 | 18 | 0.243 | 0.328 | 0.16 | CR |
| Kevin Youkilis | 114 | 24 | 20 | 0.404 | 0.509 | 1.77 | 1B-3B |
| Nick Green | 95 | 10 | 13 | 0.302 | 0.368 | 0.04 | SS |
| Jeff Bailey | 69 | 8 | 9 | 0.190 | 0.319 | 0.06 | 1B |
| Julio Lugo | 61 | 9 | 4 | 0.309 | 0.377 | -0.16 | 2B-SS |
| Rocco Baldelli | 41 | 4 | 4 | 0.205 | 0.244 | -0.18 | RF |
| George Kottaras | 37 | 4 | 4 | 0.133 | 0.243 | -0.08 | CR |
| Jed Lowrie | 20 | 0 | 0 | 0.056 | 0.150 | -0.50 | SS |
| Jonathan Van Every | 13 | 1 | 3 | 0.364 | 0.462 | 0.10 | X |
| Chris Carter | 6 | 0 | 1 | 0.000 | 0.000 | -0.04 | X |
| Gil Velazquez | 3 | 0 | 0 | 0.000 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Tim Wakefield | 52.7 | 3.59 | 8 | 0 | X | 1.12 |
| Josh Beckett | 47.7 | 5.85 | 8 | 0 | X | -1.50 |
| Jon Lester | 47.0 | 6.51 | 8 | 0 | X | -2.20 |
| Brad Penny | 43.0 | 6.07 | 8 | 0 | X | -1.57 |
| Justin Masterson | 41.3 | 4.57 | 6 | 4 | X | -0.07 |
| Ramon Ramirez | 21.0 | 0.86 | 0 | 20 | X | 1.79 |
| Hideki Okajima | 19.0 | 2.84 | 0 | 20 | X | 0.74 |
| Manny Delcarmen | 19.0 | 0.95 | 0 | 18 | X | 1.58 |
| Jonathan Papelbon | 18.0 | 1.00 | 0 | 17 | X | 1.47 |
| Takashi Saito | 15.0 | 3.60 | 0 | 15 | X | 0.32 |
| Javier Lopez | 11.7 | 9.26 | 0 | 14 | X | -1.29 |
| Hunter Jones | 9.0 | 8.00 | 0 | 8 | X | -0.73 |
| Daisuke Matsuzaka | 6.3 | 12.79 | 2 | 0 | X | -1.22 |
| Daniel Bard | 4.0 | 2.25 | 0 | 3 | X | 0.21 |
| Michael Bowden | 2.0 | 0.00 | 0 | 1 | X | 0.21 |
| Jonathan Van Every | 0.7 | 0.00 | 0 | 1 | X | 0.07 |
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