| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 174 | 30 | 13 | 0.315 | 0.408 | 0.16 | 2B |
| Jacoby Ellsbury | 174 | 20 | 13 | 0.303 | 0.333 | -0.89 | CF |
| Jason Bay | 170 | 32 | 40 | 0.294 | 0.429 | 3.30 | LF |
| David Ortiz | 161 | 14 | 15 | 0.201 | 0.317 | -0.98 | DH |
| Mike Lowell | 159 | 20 | 28 | 0.289 | 0.321 | 1.06 | 3B |
| J.D. Drew | 141 | 24 | 19 | 0.256 | 0.383 | 0.99 | RF |
| Jason Varitek | 124 | 12 | 16 | 0.231 | 0.315 | -0.16 | CR |
| Kevin Youkilis | 109 | 23 | 20 | 0.393 | 0.505 | 1.79 | 1B-3B |
| Nick Green | 95 | 10 | 13 | 0.302 | 0.368 | 0.04 | SS |
| Jeff Bailey | 69 | 8 | 9 | 0.190 | 0.319 | 0.06 | 1B |
| Julio Lugo | 57 | 8 | 4 | 0.314 | 0.386 | -0.17 | 2B-SS |
| Rocco Baldelli | 37 | 4 | 4 | 0.200 | 0.243 | -0.09 | RF |
| George Kottaras | 37 | 4 | 4 | 0.133 | 0.243 | -0.09 | CR |
| Jed Lowrie | 20 | 0 | 0 | 0.056 | 0.150 | -0.50 | SS |
| Jonathan Van Every | 13 | 1 | 3 | 0.364 | 0.462 | 0.09 | X |
| Chris Carter | 6 | 0 | 1 | 0.000 | 0.000 | -0.05 | X |
| Gil Velazquez | 3 | 0 | 0 | 0.000 | 0.333 | -0.08 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Tim Wakefield | 52.7 | 3.59 | 8 | 0 | X | 1.13 |
| Josh Beckett | 47.7 | 5.85 | 8 | 0 | X | -1.49 |
| Jon Lester | 47.0 | 6.51 | 8 | 0 | X | -2.19 |
| Justin Masterson | 41.3 | 4.57 | 6 | 4 | X | -0.06 |
| Brad Penny | 36.3 | 6.69 | 7 | 0 | X | -1.85 |
| Ramon Ramirez | 21.0 | 0.86 | 0 | 20 | X | 1.79 |
| Hideki Okajima | 18.7 | 2.89 | 0 | 19 | X | 0.70 |
| Manny Delcarmen | 18.7 | 0.96 | 0 | 17 | X | 1.54 |
| Jonathan Papelbon | 18.0 | 1.00 | 0 | 17 | X | 1.47 |
| Takashi Saito | 14.0 | 3.86 | 0 | 14 | X | 0.21 |
| Javier Lopez | 11.7 | 9.26 | 0 | 14 | X | -1.29 |
| Hunter Jones | 9.0 | 8.00 | 0 | 8 | X | -0.73 |
| Daisuke Matsuzaka | 6.3 | 12.79 | 2 | 0 | X | -1.22 |
| Daniel Bard | 3.3 | 0.00 | 0 | 2 | X | 0.35 |
| Michael Bowden | 2.0 | 0.00 | 0 | 1 | X | 0.21 |
| Jonathan Van Every | 0.7 | 0.00 | 0 | 1 | X | 0.07 |
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