| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| David Ortiz | 150 | 14 | 15 | 0.218 | 0.333 | -0.74 | DH |
| Dustin Pedroia | 149 | 29 | 12 | 0.320 | 0.409 | 0.55 | 2B |
| Jacoby Ellsbury | 148 | 19 | 11 | 0.293 | 0.324 | -0.58 | CF |
| Jason Bay | 147 | 30 | 37 | 0.319 | 0.456 | 3.33 | LF |
| Mike Lowell | 139 | 18 | 28 | 0.301 | 0.331 | 1.33 | 3B |
| J.D. Drew | 121 | 18 | 17 | 0.245 | 0.364 | 0.63 | RF |
| Kevin Youkilis | 109 | 23 | 20 | 0.393 | 0.505 | 1.77 | 1B-3B |
| Jason Varitek | 106 | 11 | 13 | 0.239 | 0.330 | -0.15 | CR |
| Nick Green | 90 | 10 | 13 | 0.293 | 0.356 | 0.15 | SS |
| Jeff Bailey | 48 | 6 | 7 | 0.175 | 0.312 | 0.16 | 1B |
| Julio Lugo | 41 | 6 | 2 | 0.270 | 0.341 | -0.19 | 2B-SS |
| George Kottaras | 34 | 4 | 3 | 0.143 | 0.265 | -0.12 | CR |
| Rocco Baldelli | 23 | 4 | 4 | 0.273 | 0.304 | 0.26 | RF |
| Jed Lowrie | 20 | 0 | 0 | 0.056 | 0.150 | -0.50 | SS |
| Jonathan Van Every | 13 | 1 | 3 | 0.364 | 0.462 | 0.09 | X |
| Chris Carter | 6 | 0 | 1 | 0.000 | 0.000 | -0.05 | X |
| Gil Velazquez | 2 | 0 | 0 | 0.000 | 0.000 | -0.05 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Tim Wakefield | 44.7 | 4.03 | 7 | 0 | X | 0.54 |
| Jon Lester | 41.3 | 6.31 | 7 | 0 | X | -1.70 |
| Josh Beckett | 40.7 | 6.42 | 7 | 0 | X | -1.77 |
| Justin Masterson | 35.0 | 4.89 | 5 | 4 | X | -0.27 |
| Brad Penny | 30.0 | 6.90 | 6 | 0 | X | -1.64 |
| Ramon Ramirez | 17.3 | 0.52 | 0 | 17 | X | 1.63 |
| Manny Delcarmen | 17.3 | 0.52 | 0 | 15 | X | 1.63 |
| Hideki Okajima | 16.3 | 3.31 | 0 | 16 | X | 0.48 |
| Jonathan Papelbon | 15.0 | 1.20 | 0 | 14 | X | 1.17 |
| Takashi Saito | 13.0 | 4.15 | 0 | 13 | X | 0.12 |
| Javier Lopez | 11.7 | 9.26 | 0 | 14 | X | -1.28 |
| Hunter Jones | 9.0 | 8.00 | 0 | 8 | X | -0.72 |
| Daisuke Matsuzaka | 6.3 | 12.79 | 2 | 0 | X | -1.22 |
| Daniel Bard | 2.0 | 0.00 | 0 | 1 | X | 0.21 |
| Michael Bowden | 2.0 | 0.00 | 0 | 1 | X | 0.21 |
| Jonathan Van Every | 0.7 | 0.00 | 0 | 1 | X | 0.07 |
_