| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 149 | 29 | 12 | 0.320 | 0.409 | 0.61 | 2B |
| David Ortiz | 146 | 13 | 15 | 0.217 | 0.336 | -0.68 | DH |
| Jacoby Ellsbury | 144 | 19 | 10 | 0.294 | 0.326 | -0.53 | CF |
| Jason Bay | 143 | 29 | 35 | 0.312 | 0.455 | 3.17 | LF |
| Mike Lowell | 135 | 18 | 28 | 0.310 | 0.341 | 1.48 | 3B |
| J.D. Drew | 118 | 18 | 17 | 0.253 | 0.373 | 0.75 | RF |
| Kevin Youkilis | 109 | 23 | 20 | 0.393 | 0.505 | 1.81 | 1B-3B |
| Jason Varitek | 106 | 11 | 13 | 0.239 | 0.330 | -0.11 | CR |
| Nick Green | 87 | 10 | 12 | 0.291 | 0.356 | 0.15 | SS |
| Jeff Bailey | 45 | 5 | 7 | 0.184 | 0.311 | 0.14 | 1B |
| Julio Lugo | 37 | 6 | 2 | 0.303 | 0.378 | -0.08 | 2B-SS |
| George Kottaras | 31 | 3 | 3 | 0.154 | 0.258 | -0.14 | CR |
| Rocco Baldelli | 23 | 4 | 4 | 0.273 | 0.304 | 0.27 | RF |
| Jed Lowrie | 20 | 0 | 0 | 0.056 | 0.150 | -0.50 | SS |
| Jonathan Van Every | 13 | 1 | 3 | 0.364 | 0.462 | 0.10 | X |
| Chris Carter | 6 | 0 | 1 | 0.000 | 0.000 | -0.04 | X |
| Gil Velazquez | 2 | 0 | 0 | 0.000 | 0.000 | -0.05 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 41.3 | 6.31 | 7 | 0 | X | -1.76 |
| Josh Beckett | 40.7 | 6.42 | 7 | 0 | X | -1.83 |
| Tim Wakefield | 40.0 | 2.92 | 6 | 0 | X | 1.46 |
| Justin Masterson | 35.0 | 4.89 | 5 | 4 | X | -0.32 |
| Brad Penny | 30.0 | 6.90 | 6 | 0 | X | -1.69 |
| Manny Delcarmen | 17.3 | 0.52 | 0 | 15 | X | 1.61 |
| Ramon Ramirez | 17.3 | 0.52 | 0 | 17 | X | 1.61 |
| Hideki Okajima | 16.3 | 3.31 | 0 | 16 | X | 0.45 |
| Jonathan Papelbon | 15.0 | 1.20 | 0 | 14 | X | 1.15 |
| Takashi Saito | 12.0 | 4.50 | 0 | 12 | X | 0.00 |
| Javier Lopez | 11.7 | 9.26 | 0 | 14 | X | -1.30 |
| Hunter Jones | 8.7 | 7.27 | 0 | 7 | X | -0.56 |
| Daisuke Matsuzaka | 6.3 | 12.79 | 2 | 0 | X | -1.23 |
| Michael Bowden | 2.0 | 0.00 | 0 | 1 | X | 0.21 |
| Jonathan Van Every | 0.7 | 0.00 | 0 | 1 | X | 0.07 |
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