| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 147 | 29 | 12 | 0.325 | 0.415 | 0.69 | 2B |
| David Ortiz | 138 | 12 | 14 | 0.219 | 0.333 | -0.67 | DH |
| Jacoby Ellsbury | 135 | 18 | 10 | 0.291 | 0.326 | -0.38 | CF |
| Jason Bay | 135 | 28 | 33 | 0.317 | 0.467 | 3.08 | LF |
| Mike Lowell | 127 | 18 | 28 | 0.314 | 0.346 | 1.70 | 3B |
| J.D. Drew | 110 | 16 | 16 | 0.250 | 0.373 | 0.65 | RF |
| Kevin Youkilis | 109 | 23 | 20 | 0.393 | 0.505 | 1.83 | 1B-3B |
| Jason Varitek | 98 | 10 | 11 | 0.226 | 0.327 | -0.21 | CR |
| Nick Green | 80 | 9 | 11 | 0.274 | 0.338 | 0.13 | SS |
| Jeff Bailey | 37 | 4 | 7 | 0.194 | 0.324 | 0.24 | 1B |
| George Kottaras | 31 | 3 | 3 | 0.154 | 0.258 | -0.13 | CR |
| Julio Lugo | 30 | 6 | 2 | 0.357 | 0.400 | 0.10 | 2B-SS |
| Rocco Baldelli | 23 | 4 | 4 | 0.273 | 0.304 | 0.27 | RF |
| Jed Lowrie | 20 | 0 | 0 | 0.056 | 0.150 | -0.49 | SS |
| Jonathan Van Every | 13 | 1 | 3 | 0.364 | 0.462 | 0.10 | X |
| Chris Carter | 6 | 0 | 1 | 0.000 | 0.000 | -0.04 | X |
| Gil Velazquez | 2 | 0 | 0 | 0.000 | 0.000 | -0.05 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 41.3 | 6.31 | 7 | 0 | X | -1.76 |
| Tim Wakefield | 40.0 | 2.92 | 6 | 0 | X | 1.46 |
| Josh Beckett | 34.7 | 6.75 | 6 | 0 | X | -1.83 |
| Brad Penny | 30.0 | 6.90 | 6 | 0 | X | -1.69 |
| Justin Masterson | 29.0 | 5.28 | 4 | 4 | X | -0.53 |
| Manny Delcarmen | 16.3 | 0.55 | 0 | 14 | X | 1.50 |
| Ramon Ramirez | 16.0 | 0.56 | 0 | 15 | X | 1.47 |
| Hideki Okajima | 14.7 | 3.68 | 0 | 15 | X | 0.28 |
| Jonathan Papelbon | 13.0 | 1.38 | 0 | 12 | X | 0.94 |
| Takashi Saito | 12.0 | 4.50 | 0 | 12 | X | 0.00 |
| Javier Lopez | 11.7 | 9.26 | 0 | 14 | X | -1.30 |
| Hunter Jones | 8.7 | 7.27 | 0 | 7 | X | -0.56 |
| Daisuke Matsuzaka | 6.3 | 12.79 | 2 | 0 | X | -1.23 |
| Michael Bowden | 2.0 | 0.00 | 0 | 1 | X | 0.21 |
| Jonathan Van Every | 0.7 | 0.00 | 0 | 1 | X | 0.07 |
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