| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 142 | 28 | 12 | 0.336 | 0.423 | 0.70 | 2B |
| David Ortiz | 133 | 12 | 14 | 0.218 | 0.331 | -0.55 | DH |
| Jacoby Ellsbury | 130 | 17 | 10 | 0.293 | 0.323 | -0.37 | CF |
| Jason Bay | 130 | 27 | 32 | 0.323 | 0.477 | 2.99 | LF |
| Mike Lowell | 123 | 18 | 26 | 0.308 | 0.341 | 1.59 | 3B |
| J.D. Drew | 110 | 16 | 16 | 0.250 | 0.373 | 0.65 | RF |
| Kevin Youkilis | 109 | 23 | 20 | 0.393 | 0.505 | 1.83 | 1B-3B |
| Jason Varitek | 95 | 10 | 11 | 0.232 | 0.326 | -0.14 | CR |
| Nick Green | 79 | 9 | 11 | 0.278 | 0.342 | 0.15 | SS |
| Jeff Bailey | 33 | 4 | 7 | 0.179 | 0.303 | 0.34 | 1B |
| George Kottaras | 30 | 3 | 3 | 0.160 | 0.267 | -0.11 | CR |
| Julio Lugo | 26 | 5 | 1 | 0.333 | 0.385 | -0.01 | 2B-SS |
| Jed Lowrie | 20 | 0 | 0 | 0.056 | 0.150 | -0.49 | SS |
| Rocco Baldelli | 18 | 3 | 3 | 0.235 | 0.278 | 0.19 | RF |
| Jonathan Van Every | 13 | 1 | 3 | 0.364 | 0.462 | 0.10 | X |
| Chris Carter | 6 | 0 | 1 | 0.000 | 0.000 | -0.04 | X |
| Gil Velazquez | 2 | 0 | 0 | 0.000 | 0.000 | -0.05 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Tim Wakefield | 40.0 | 2.92 | 6 | 0 | X | 1.45 |
| Jon Lester | 37.0 | 5.11 | 6 | 0 | X | -0.54 |
| Josh Beckett | 34.7 | 6.75 | 6 | 0 | X | -1.83 |
| Brad Penny | 30.0 | 6.90 | 6 | 0 | X | -1.69 |
| Justin Masterson | 29.0 | 5.28 | 4 | 4 | X | -0.54 |
| Ramon Ramirez | 16.0 | 0.56 | 0 | 15 | X | 1.46 |
| Manny Delcarmen | 15.3 | 0.59 | 0 | 13 | X | 1.39 |
| Hideki Okajima | 14.7 | 3.68 | 0 | 15 | X | 0.27 |
| Jonathan Papelbon | 13.0 | 1.38 | 0 | 12 | X | 0.94 |
| Takashi Saito | 11.0 | 4.09 | 0 | 11 | X | 0.10 |
| Javier Lopez | 9.7 | 10.24 | 0 | 13 | X | -1.30 |
| Hunter Jones | 8.0 | 3.38 | 0 | 6 | X | 0.21 |
| Daisuke Matsuzaka | 6.3 | 12.79 | 2 | 0 | X | -1.23 |
| Michael Bowden | 2.0 | 0.00 | 0 | 1 | X | 0.21 |
| Jonathan Van Every | 0.7 | 0.00 | 0 | 1 | X | 0.07 |
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