| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 128 | 25 | 8 | 0.321 | 0.414 | 0.31 | 2B |
| Jacoby Ellsbury | 125 | 16 | 9 | 0.288 | 0.320 | -0.46 | CF |
| David Ortiz | 124 | 11 | 14 | 0.223 | 0.331 | -0.44 | DH |
| Jason Bay | 117 | 23 | 25 | 0.322 | 0.487 | 2.15 | LF |
| Mike Lowell | 111 | 15 | 26 | 0.302 | 0.333 | 1.57 | 3B |
| Kevin Youkilis | 109 | 23 | 20 | 0.393 | 0.505 | 1.82 | 1B-3B |
| J.D. Drew | 98 | 14 | 14 | 0.259 | 0.388 | 0.52 | RF |
| Jason Varitek | 87 | 10 | 11 | 0.213 | 0.310 | 0.06 | CR |
| Nick Green | 71 | 8 | 11 | 0.281 | 0.352 | 0.24 | SS |
| George Kottaras | 26 | 2 | 1 | 0.143 | 0.269 | -0.33 | CR |
| Jeff Bailey | 21 | 3 | 4 | 0.118 | 0.286 | 0.22 | 1B |
| Jed Lowrie | 20 | 0 | 0 | 0.056 | 0.150 | -0.49 | SS |
| Julio Lugo | 16 | 1 | 1 | 0.214 | 0.312 | -0.18 | 2B-SS |
| Rocco Baldelli | 14 | 2 | 1 | 0.231 | 0.286 | -0.03 | RF |
| Jonathan Van Every | 10 | 1 | 2 | 0.250 | 0.400 | 0.07 | X |
| Chris Carter | 6 | 0 | 1 | 0.000 | 0.000 | -0.04 | X |
| Gil Velazquez | 2 | 0 | 0 | 0.000 | 0.000 | -0.05 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 37.0 | 5.11 | 6 | 0 | X | -0.51 |
| Josh Beckett | 34.7 | 6.75 | 6 | 0 | X | -1.81 |
| Tim Wakefield | 34.0 | 2.91 | 5 | 0 | X | 1.27 |
| Brad Penny | 23.7 | 7.61 | 5 | 0 | X | -1.71 |
| Justin Masterson | 22.7 | 4.37 | 3 | 4 | X | 0.08 |
| Ramon Ramirez | 15.3 | 0.59 | 0 | 14 | X | 1.41 |
| Manny Delcarmen | 14.3 | 0.63 | 0 | 12 | X | 1.30 |
| Hideki Okajima | 13.7 | 3.95 | 0 | 14 | X | 0.18 |
| Jonathan Papelbon | 12.0 | 1.50 | 0 | 11 | X | 0.84 |
| Takashi Saito | 10.0 | 4.50 | 0 | 10 | X | 0.00 |
| Javier Lopez | 7.7 | 9.39 | 0 | 11 | X | -0.87 |
| Daisuke Matsuzaka | 6.3 | 12.79 | 2 | 0 | X | -1.22 |
| Hunter Jones | 6.3 | 2.84 | 0 | 5 | X | 0.25 |
| Michael Bowden | 2.0 | 0.00 | 0 | 1 | X | 0.21 |
| Jonathan Van Every | 0.7 | 0.00 | 0 | 1 | X | 0.07 |
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