| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Grady Sizemore | 745 | 101 | 90 | 0.268 | 0.374 | 1.76 | CF |
| Jhonny Peralta | 664 | 105 | 89 | 0.276 | 0.330 | 4.06 | SS |
| Ryan Garko | 563 | 65 | 92 | 0.273 | 0.346 | 2.66 | 1B-DH |
| Ben Francisco | 499 | 65 | 54 | 0.266 | 0.331 | 0.24 | LF-RF-DH |
| Franklin Gutierrez | 440 | 54 | 42 | 0.247 | 0.305 | -0.73 | RF-CF-LF |
| Asdrubal Cabrera | 418 | 47 | 47 | 0.259 | 0.337 | -0.39 | 2B-SS |
| Kelly Shoppach | 403 | 69 | 55 | 0.261 | 0.345 | 3.12 | CR |
| Jamey Carroll | 402 | 57 | 36 | 0.275 | 0.346 | -0.11 | 2B-3B |
| David Dellucci | 375 | 39 | 47 | 0.238 | 0.307 | -0.18 | LF-DH |
| Shin-Soo Choo | 370 | 68 | 66 | 0.309 | 0.397 | 4.98 | RF-LF-DH |
| Casey Blake | 368 | 46 | 58 | 0.289 | 0.364 | 1.88 | 3B |
| Victor Martinez | 294 | 31 | 35 | 0.278 | 0.337 | -0.29 | CR-1B |
| Andy Marte | 257 | 22 | 17 | 0.220 | 0.261 | -2.22 | 3B |
| Travis Hafner | 234 | 22 | 24 | 0.196 | 0.303 | -0.92 | DH |
| Jason Michaels | 67 | 2 | 9 | 0.207 | 0.254 | -0.49 | RF-LF |
| Sal Fasano | 54 | 5 | 6 | 0.261 | 0.333 | -0.17 | CR |
| Michael Aubrey | 50 | 2 | 3 | 0.200 | 0.280 | -0.70 | 1B |
| Josh Barfield | 33 | 2 | 2 | 0.182 | 0.182 | -0.39 | X |
| Andy Gonzalez | 30 | 1 | 2 | 0.208 | 0.367 | -0.42 | X |
| Jorge Velandia | 9 | 1 | 0 | 0.375 | 0.444 | -0.12 | X |
| Jason Tyner | 3 | 0 | 0 | 0.000 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Cliff Lee | 223.3 | 2.54 | 31 | 0 | X | 9.41 |
| Paul Byrd | 131.0 | 4.53 | 22 | 0 | X | -0.58 |
| C.C. Sabathia | 122.3 | 3.83 | 18 | 0 | X | 1.48 |
| Jeremy Sowers | 121.0 | 5.58 | 22 | 0 | X | -3.49 |
| Fausto Carmona | 120.7 | 5.44 | 22 | 0 | X | -3.10 |
| Aaron Laffey | 93.7 | 4.23 | 16 | 0 | X | 0.25 |
| Rafael Perez | 76.3 | 3.42 | 0 | 73 | X | 1.65 |
| Rafael Betancourt | 71.0 | 5.20 | 0 | 69 | X | -1.41 |
| Jensen Lewis | 66.0 | 3.82 | 0 | 51 | X | 0.81 |
| Masahide Kobayashi | 55.7 | 4.53 | 0 | 57 | X | -0.24 |
| Zach Jackson | 54.7 | 5.60 | 9 | 0 | X | -1.60 |
| Edward Mujica | 38.7 | 6.52 | 0 | 33 | X | -1.96 |
| Jake Westbrook | 34.7 | 3.12 | 5 | 0 | X | 0.99 |
| Anthony Reyes | 34.3 | 1.83 | 6 | 0 | X | 2.01 |
| Juan Rincon | 27.3 | 5.60 | 0 | 23 | X | -0.80 |
| Scott Lewis | 24.0 | 2.62 | 4 | 0 | X | 0.96 |
| Matt Ginter | 21.0 | 5.14 | 4 | 0 | X | -0.39 |
| Tom Mastny | 20.0 | 10.80 | 1 | 13 | X | -3.01 |
| Jorge Julio | 17.7 | 5.60 | 0 | 15 | X | -0.52 |
| Joe Borowski | 16.7 | 7.56 | 0 | 18 | X | -1.25 |
| Scott Elarton | 15.3 | 3.52 | 0 | 8 | X | 0.29 |
| Bryan Bullington | 14.7 | 4.91 | 2 | 1 | X | -0.19 |
| Brendan Donnelly | 13.7 | 8.56 | 0 | 15 | X | -1.34 |
| Craig Breslow | 8.3 | 3.24 | 0 | 7 | X | 0.21 |
| Rick Bauer | 6.0 | 13.50 | 0 | 4 | X | -1.28 |
| Rich Rundles | 5.0 | 1.80 | 0 | 8 | X | 0.30 |
| Brian Slocum | 2.0 | 27.00 | 0 | 2 | X | -1.06 |
| Jonathan Meloan | 2.0 | 0.00 | 0 | 2 | X | 0.20 |
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