| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Grady Sizemore | 716 | 97 | 89 | 0.271 | 0.377 | 1.98 | CF |
| Jhonny Peralta | 636 | 102 | 85 | 0.272 | 0.325 | 4.05 | SS |
| Ryan Garko | 542 | 62 | 86 | 0.267 | 0.343 | 2.26 | 1B-DH |
| Ben Francisco | 476 | 62 | 53 | 0.272 | 0.334 | 0.41 | LF-RF-DH |
| Franklin Gutierrez | 424 | 52 | 39 | 0.246 | 0.302 | -0.84 | RF-CF-LF |
| Asdrubal Cabrera | 406 | 43 | 44 | 0.255 | 0.335 | -0.82 | 2B-SS |
| Kelly Shoppach | 388 | 68 | 55 | 0.266 | 0.343 | 3.41 | CR |
| Jamey Carroll | 379 | 55 | 32 | 0.271 | 0.348 | -0.15 | 2B-3B |
| Casey Blake | 368 | 46 | 58 | 0.289 | 0.364 | 1.90 | 3B |
| David Dellucci | 368 | 38 | 47 | 0.239 | 0.307 | -0.09 | LF-DH |
| Shin-Soo Choo | 350 | 61 | 60 | 0.308 | 0.397 | 4.13 | RF-LF-DH |
| Victor Martinez | 280 | 29 | 33 | 0.278 | 0.339 | -0.35 | CR-1B |
| Andy Marte | 256 | 22 | 17 | 0.221 | 0.262 | -2.18 | 3B |
| Travis Hafner | 223 | 22 | 24 | 0.202 | 0.314 | -0.64 | DH |
| Jason Michaels | 67 | 2 | 9 | 0.207 | 0.254 | -0.49 | RF-LF |
| Sal Fasano | 54 | 5 | 6 | 0.261 | 0.333 | -0.17 | CR |
| Michael Aubrey | 50 | 2 | 3 | 0.200 | 0.280 | -0.70 | 1B |
| Andy Gonzalez | 30 | 1 | 2 | 0.208 | 0.367 | -0.42 | X |
| Josh Barfield | 18 | 1 | 0 | 0.056 | 0.056 | -0.34 | X |
| Jorge Velandia | 9 | 1 | 0 | 0.375 | 0.444 | -0.12 | X |
| Jason Tyner | 3 | 0 | 0 | 0.000 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Cliff Lee | 216.3 | 2.41 | 30 | 0 | X | 9.64 |
| Paul Byrd | 131.0 | 4.53 | 22 | 0 | X | -0.65 |
| C.C. Sabathia | 122.3 | 3.83 | 18 | 0 | X | 1.42 |
| Fausto Carmona | 119.7 | 5.19 | 21 | 0 | X | -2.42 |
| Jeremy Sowers | 115.0 | 5.48 | 21 | 0 | X | -3.10 |
| Aaron Laffey | 93.7 | 4.23 | 16 | 0 | X | 0.21 |
| Rafael Perez | 75.0 | 3.24 | 0 | 70 | X | 1.89 |
| Rafael Betancourt | 68.7 | 5.24 | 0 | 67 | X | -1.48 |
| Jensen Lewis | 63.3 | 3.84 | 0 | 49 | X | 0.72 |
| Masahide Kobayashi | 55.7 | 4.53 | 0 | 57 | X | -0.27 |
| Zach Jackson | 47.7 | 6.04 | 8 | 0 | X | -1.91 |
| Edward Mujica | 37.3 | 6.51 | 0 | 32 | X | -1.90 |
| Jake Westbrook | 34.7 | 3.12 | 5 | 0 | X | 0.98 |
| Anthony Reyes | 34.3 | 1.83 | 6 | 0 | X | 1.99 |
| Juan Rincon | 26.3 | 5.13 | 0 | 22 | X | -0.49 |
| Matt Ginter | 21.0 | 5.14 | 4 | 0 | X | -0.40 |
| Scott Lewis | 19.0 | 1.42 | 3 | 0 | X | 1.29 |
| Tom Mastny | 18.0 | 11.50 | 1 | 12 | X | -3.01 |
| Jorge Julio | 17.7 | 5.60 | 0 | 15 | X | -0.53 |
| Joe Borowski | 16.7 | 7.56 | 0 | 18 | X | -1.26 |
| Scott Elarton | 15.3 | 3.52 | 0 | 8 | X | 0.29 |
| Brendan Donnelly | 12.0 | 8.25 | 0 | 13 | X | -1.10 |
| Craig Breslow | 8.3 | 3.24 | 0 | 7 | X | 0.21 |
| Rick Bauer | 6.0 | 13.50 | 0 | 4 | X | -1.28 |
| Bryan Bullington | 4.7 | 11.57 | 1 | 0 | X | -0.79 |
| Rich Rundles | 3.3 | 2.70 | 0 | 6 | X | 0.13 |
| Jonathan Meloan | 2.0 | 0.00 | 0 | 2 | X | 0.20 |
| Brian Slocum | 2.0 | 27.00 | 0 | 2 | X | -1.06 |
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