| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Grady Sizemore | 701 | 96 | 89 | 0.274 | 0.381 | 2.18 | CF |
| Jhonny Peralta | 622 | 100 | 84 | 0.274 | 0.323 | 4.02 | SS |
| Ryan Garko | 529 | 60 | 81 | 0.259 | 0.336 | 1.79 | 1B-DH |
| Ben Francisco | 467 | 61 | 52 | 0.267 | 0.328 | 0.38 | LF-RF-DH |
| Franklin Gutierrez | 420 | 51 | 39 | 0.248 | 0.302 | -0.88 | RF-CF-LF |
| Asdrubal Cabrera | 393 | 41 | 40 | 0.245 | 0.326 | -1.16 | 2B-SS |
| Kelly Shoppach | 379 | 66 | 55 | 0.269 | 0.343 | 3.38 | CR |
| Jamey Carroll | 369 | 53 | 31 | 0.272 | 0.347 | -0.26 | 2B-3B |
| Casey Blake | 368 | 46 | 58 | 0.289 | 0.364 | 1.87 | 3B |
| David Dellucci | 368 | 38 | 47 | 0.239 | 0.307 | -0.13 | LF-DH |
| Shin-Soo Choo | 335 | 58 | 57 | 0.307 | 0.394 | 3.83 | RF-LF-DH |
| Victor Martinez | 275 | 26 | 32 | 0.273 | 0.331 | -0.67 | CR-1B |
| Andy Marte | 251 | 21 | 16 | 0.216 | 0.255 | -2.29 | 3B |
| Travis Hafner | 214 | 22 | 23 | 0.210 | 0.318 | -0.54 | DH |
| Jason Michaels | 67 | 2 | 9 | 0.207 | 0.254 | -0.49 | RF-LF |
| Sal Fasano | 54 | 5 | 6 | 0.261 | 0.333 | -0.17 | CR |
| Michael Aubrey | 50 | 2 | 3 | 0.200 | 0.280 | -0.70 | 1B |
| Andy Gonzalez | 30 | 1 | 2 | 0.208 | 0.367 | -0.42 | X |
| Josh Barfield | 13 | 1 | 0 | 0.077 | 0.077 | -0.21 | X |
| Jorge Velandia | 9 | 1 | 0 | 0.375 | 0.444 | -0.12 | X |
| Jason Tyner | 3 | 0 | 0 | 0.000 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Cliff Lee | 216.3 | 2.41 | 30 | 0 | X | 9.69 |
| Paul Byrd | 131.0 | 4.53 | 22 | 0 | X | -0.61 |
| C.C. Sabathia | 122.3 | 3.83 | 18 | 0 | X | 1.45 |
| Fausto Carmona | 119.7 | 5.19 | 21 | 0 | X | -2.39 |
| Jeremy Sowers | 109.0 | 5.70 | 20 | 0 | X | -3.47 |
| Aaron Laffey | 93.7 | 4.23 | 16 | 0 | X | 0.23 |
| Rafael Perez | 74.3 | 3.03 | 0 | 68 | X | 2.27 |
| Rafael Betancourt | 66.3 | 5.29 | 0 | 65 | X | -1.48 |
| Jensen Lewis | 61.3 | 3.96 | 0 | 47 | X | 0.53 |
| Masahide Kobayashi | 55.7 | 4.53 | 0 | 57 | X | -0.25 |
| Zach Jackson | 41.7 | 6.48 | 7 | 0 | X | -2.09 |
| Edward Mujica | 36.3 | 6.69 | 0 | 31 | X | -2.00 |
| Jake Westbrook | 34.7 | 3.12 | 5 | 0 | X | 0.99 |
| Anthony Reyes | 34.3 | 1.83 | 6 | 0 | X | 2.00 |
| Juan Rincon | 24.3 | 4.81 | 0 | 21 | X | -0.27 |
| Matt Ginter | 21.0 | 5.14 | 4 | 0 | X | -0.40 |
| Tom Mastny | 18.0 | 11.50 | 1 | 12 | X | -3.01 |
| Jorge Julio | 17.7 | 5.60 | 0 | 15 | X | -0.52 |
| Joe Borowski | 16.7 | 7.56 | 0 | 18 | X | -1.25 |
| Scott Elarton | 15.3 | 3.52 | 0 | 8 | X | 0.29 |
| Scott Lewis | 14.0 | 0.00 | 2 | 0 | X | 1.42 |
| Brendan Donnelly | 11.0 | 9.00 | 0 | 12 | X | -1.20 |
| Craig Breslow | 8.3 | 3.24 | 0 | 7 | X | 0.21 |
| Rick Bauer | 6.0 | 13.50 | 0 | 4 | X | -1.28 |
| Bryan Bullington | 4.7 | 11.57 | 1 | 0 | X | -0.79 |
| Rich Rundles | 3.3 | 2.70 | 0 | 6 | X | 0.13 |
| Brian Slocum | 2.0 | 27.00 | 0 | 2 | X | -1.06 |
| Jonathan Meloan | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
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