| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Grady Sizemore | 686 | 92 | 87 | 0.271 | 0.379 | 1.94 | CF |
| Jhonny Peralta | 608 | 97 | 82 | 0.274 | 0.321 | 3.86 | SS |
| Ryan Garko | 523 | 59 | 77 | 0.254 | 0.333 | 1.43 | 1B-DH |
| Ben Francisco | 460 | 59 | 52 | 0.270 | 0.330 | 0.35 | LF-RF-DH |
| Franklin Gutierrez | 410 | 49 | 39 | 0.245 | 0.298 | -0.83 | RF-CF-LF |
| Asdrubal Cabrera | 381 | 39 | 38 | 0.245 | 0.328 | -1.28 | 2B-SS |
| Kelly Shoppach | 368 | 63 | 55 | 0.272 | 0.342 | 3.35 | CR |
| Casey Blake | 368 | 46 | 58 | 0.289 | 0.364 | 1.88 | 3B |
| David Dellucci | 365 | 38 | 47 | 0.242 | 0.310 | -0.04 | LF-DH |
| Jamey Carroll | 361 | 52 | 30 | 0.272 | 0.349 | -0.26 | 2B-3B |
| Shin-Soo Choo | 325 | 56 | 51 | 0.303 | 0.394 | 3.25 | RF-LF-DH |
| Victor Martinez | 263 | 23 | 28 | 0.269 | 0.327 | -1.11 | CR-1B |
| Andy Marte | 246 | 21 | 15 | 0.217 | 0.256 | -2.26 | 3B |
| Travis Hafner | 206 | 21 | 22 | 0.211 | 0.316 | -0.55 | DH |
| Jason Michaels | 67 | 2 | 9 | 0.207 | 0.254 | -0.49 | RF-LF |
| Sal Fasano | 54 | 5 | 6 | 0.261 | 0.333 | -0.17 | CR |
| Michael Aubrey | 47 | 2 | 3 | 0.214 | 0.298 | -0.63 | 1B |
| Andy Gonzalez | 30 | 1 | 2 | 0.208 | 0.367 | -0.42 | X |
| Josh Barfield | 13 | 1 | 0 | 0.077 | 0.077 | -0.21 | X |
| Jorge Velandia | 9 | 1 | 0 | 0.375 | 0.444 | -0.12 | X |
| Jason Tyner | 3 | 0 | 0 | 0.000 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Cliff Lee | 210.0 | 2.36 | 29 | 0 | X | 9.67 |
| Paul Byrd | 131.0 | 4.53 | 22 | 0 | X | -0.62 |
| C.C. Sabathia | 122.3 | 3.83 | 18 | 0 | X | 1.44 |
| Fausto Carmona | 113.3 | 5.16 | 20 | 0 | X | -2.20 |
| Jeremy Sowers | 109.0 | 5.70 | 20 | 0 | X | -3.48 |
| Aaron Laffey | 93.7 | 4.23 | 16 | 0 | X | 0.22 |
| Rafael Perez | 73.0 | 3.08 | 0 | 66 | X | 2.13 |
| Rafael Betancourt | 65.0 | 5.12 | 0 | 63 | X | -1.20 |
| Jensen Lewis | 58.3 | 4.17 | 0 | 45 | X | 0.22 |
| Masahide Kobayashi | 55.7 | 4.53 | 0 | 57 | X | -0.25 |
| Zach Jackson | 36.3 | 5.70 | 6 | 0 | X | -1.16 |
| Jake Westbrook | 34.7 | 3.12 | 5 | 0 | X | 0.98 |
| Anthony Reyes | 34.3 | 1.83 | 6 | 0 | X | 2.00 |
| Edward Mujica | 33.7 | 6.95 | 0 | 28 | X | -2.06 |
| Juan Rincon | 24.0 | 4.88 | 0 | 20 | X | -0.30 |
| Matt Ginter | 21.0 | 5.14 | 4 | 0 | X | -0.40 |
| Jorge Julio | 17.7 | 5.60 | 0 | 15 | X | -0.52 |
| Tom Mastny | 17.0 | 12.18 | 1 | 11 | X | -3.11 |
| Joe Borowski | 16.7 | 7.56 | 0 | 18 | X | -1.26 |
| Scott Elarton | 15.3 | 3.52 | 0 | 8 | X | 0.29 |
| Scott Lewis | 14.0 | 0.00 | 2 | 0 | X | 1.41 |
| Brendan Donnelly | 10.0 | 9.90 | 0 | 11 | X | -1.30 |
| Craig Breslow | 8.3 | 3.24 | 0 | 7 | X | 0.21 |
| Rick Bauer | 6.0 | 13.50 | 0 | 4 | X | -1.28 |
| Bryan Bullington | 4.7 | 11.57 | 1 | 0 | X | -0.79 |
| Rich Rundles | 3.0 | 3.00 | 0 | 5 | X | 0.09 |
| Brian Slocum | 2.0 | 27.00 | 0 | 2 | X | -1.06 |
| Jonathan Meloan | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
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