| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Orlando Cabrera | 577 | 76 | 50 | 0.272 | 0.326 | -0.98 | SS |
| Carlos Quentin | 535 | 92 | 96 | 0.293 | 0.398 | 6.56 | LF |
| Jermaine Dye | 502 | 80 | 81 | 0.295 | 0.349 | 4.54 | RF |
| Nick Swisher | 495 | 77 | 63 | 0.237 | 0.354 | 2.51 | 1B-CF-LF-RF |
| Jim Thome | 469 | 73 | 73 | 0.250 | 0.375 | 3.78 | DH |
| A.J. Pierzynski | 459 | 55 | 53 | 0.294 | 0.322 | 0.03 | CR |
| Paul Konerko | 406 | 48 | 44 | 0.228 | 0.340 | -0.34 | 1B |
| Alexei Ramirez | 371 | 46 | 57 | 0.308 | 0.323 | 1.68 | 2B-SS-CF |
| Joe Crede | 349 | 39 | 54 | 0.253 | 0.321 | 1.17 | 3B |
| Juan Uribe | 249 | 31 | 26 | 0.243 | 0.297 | -0.15 | 3B-2B |
| Brian Anderson | 160 | 16 | 21 | 0.240 | 0.275 | -0.06 | CF |
| Toby Hall | 107 | 7 | 6 | 0.286 | 0.336 | -1.27 | CR |
| Dewayne Wise | 71 | 10 | 7 | 0.284 | 0.310 | 0.04 | LF-CF |
| Pablo Ozuna | 69 | 5 | 6 | 0.281 | 0.304 | -0.54 | 2B |
| Ken Griffey | 58 | 7 | 7 | 0.260 | 0.345 | 0.04 | RF |
| Josh Fields | 25 | 2 | 2 | 0.182 | 0.280 | -0.20 | 3B |
| Chris Getz | 7 | 0 | 1 | 0.286 | 0.286 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Mark Buehrle | 168.0 | 3.91 | 26 | 0 | X | 1.40 |
| Javier Vazquez | 164.0 | 4.34 | 25 | 0 | X | -0.26 |
| John Danks | 156.7 | 3.10 | 26 | 0 | X | 4.26 |
| Gavin Floyd | 152.3 | 3.78 | 25 | 0 | X | 1.73 |
| Jose Contreras | 121.0 | 4.54 | 20 | 0 | X | -0.76 |
| Octavio Dotel | 55.7 | 3.72 | 0 | 60 | X | 0.71 |
| Matt Thornton | 52.7 | 2.73 | 0 | 57 | X | 1.88 |
| Bobby Jenks | 45.3 | 1.79 | 0 | 45 | X | 2.62 |
| Nick Masset | 44.7 | 4.84 | 1 | 31 | X | -0.59 |
| Boone Logan | 40.3 | 4.91 | 0 | 48 | X | -0.60 |
| Scott Linebrink | 39.0 | 2.31 | 0 | 42 | X | 1.78 |
| D.J. Carrasco | 25.3 | 2.49 | 0 | 17 | X | 1.05 |
| Adam Russell | 21.3 | 4.64 | 0 | 17 | X | -0.19 |
| Clayton Richard | 20.0 | 6.75 | 4 | 1 | X | -1.16 |
| Ehren Wassermann | 15.0 | 7.80 | 0 | 17 | X | -1.24 |
| Mike MacDougal | 8.7 | 2.08 | 0 | 8 | X | 0.44 |
| Horacio Ramirez | 7.3 | 6.14 | 0 | 7 | X | -0.32 |
| Lance Broadway | 5.7 | 3.18 | 1 | 1 | X | 0.14 |
| Esteban Loaiza | 3.0 | 3.00 | 0 | 3 | X | 0.09 |
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