| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Orlando Cabrera | 568 | 74 | 50 | 0.270 | 0.322 | -0.97 | SS |
| Carlos Quentin | 525 | 90 | 96 | 0.297 | 0.398 | 6.60 | LF |
| Jermaine Dye | 498 | 80 | 81 | 0.297 | 0.351 | 4.64 | RF |
| Nick Swisher | 486 | 74 | 59 | 0.235 | 0.354 | 1.99 | 1B-CF-LF-RF |
| Jim Thome | 465 | 72 | 73 | 0.251 | 0.372 | 3.77 | DH |
| A.J. Pierzynski | 449 | 53 | 50 | 0.289 | 0.318 | -0.24 | CR |
| Paul Konerko | 401 | 47 | 43 | 0.225 | 0.337 | -0.43 | 1B |
| Alexei Ramirez | 363 | 44 | 52 | 0.309 | 0.325 | 1.14 | 2B-SS-CF |
| Joe Crede | 349 | 39 | 54 | 0.253 | 0.321 | 1.17 | 3B |
| Juan Uribe | 241 | 30 | 24 | 0.233 | 0.286 | -0.27 | 3B-2B |
| Brian Anderson | 158 | 15 | 21 | 0.236 | 0.272 | -0.11 | CF |
| Toby Hall | 107 | 7 | 6 | 0.286 | 0.336 | -1.27 | CR |
| Pablo Ozuna | 69 | 5 | 6 | 0.281 | 0.304 | -0.54 | 2B |
| Dewayne Wise | 69 | 10 | 7 | 0.292 | 0.319 | 0.09 | LF-CF |
| Ken Griffey | 49 | 3 | 4 | 0.209 | 0.286 | -0.47 | RF |
| Josh Fields | 25 | 2 | 2 | 0.182 | 0.280 | -0.20 | 3B |
| Chris Getz | 6 | 0 | 1 | 0.333 | 0.333 | -0.04 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Mark Buehrle | 168.0 | 3.91 | 26 | 0 | X | 1.39 |
| Javier Vazquez | 164.0 | 4.34 | 25 | 0 | X | -0.27 |
| John Danks | 150.3 | 3.05 | 25 | 0 | X | 4.25 |
| Gavin Floyd | 146.3 | 3.75 | 24 | 0 | X | 1.75 |
| Jose Contreras | 121.0 | 4.54 | 20 | 0 | X | -0.77 |
| Octavio Dotel | 55.7 | 3.23 | 0 | 59 | X | 1.34 |
| Matt Thornton | 52.0 | 2.77 | 0 | 56 | X | 1.81 |
| Bobby Jenks | 45.3 | 1.79 | 0 | 45 | X | 2.62 |
| Nick Masset | 44.7 | 4.84 | 1 | 31 | X | -0.60 |
| Boone Logan | 40.3 | 4.91 | 0 | 48 | X | -0.61 |
| Scott Linebrink | 39.0 | 2.31 | 0 | 42 | X | 1.78 |
| D.J. Carrasco | 25.3 | 2.49 | 0 | 17 | X | 1.05 |
| Clayton Richard | 20.0 | 6.75 | 4 | 1 | X | -1.16 |
| Adam Russell | 18.3 | 5.40 | 0 | 15 | X | -0.49 |
| Ehren Wassermann | 15.0 | 7.80 | 0 | 17 | X | -1.24 |
| Mike MacDougal | 8.7 | 2.08 | 0 | 8 | X | 0.44 |
| Lance Broadway | 5.7 | 3.18 | 1 | 1 | X | 0.14 |
| Horacio Ramirez | 5.3 | 3.38 | 0 | 5 | X | 0.11 |
| Esteban Loaiza | 3.0 | 3.00 | 0 | 3 | X | 0.09 |
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