| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Orlando Cabrera | 549 | 72 | 48 | 0.268 | 0.322 | -0.93 | SS |
| Carlos Quentin | 506 | 85 | 90 | 0.288 | 0.387 | 5.91 | LF |
| Jermaine Dye | 481 | 77 | 78 | 0.302 | 0.358 | 4.42 | RF |
| Nick Swisher | 473 | 71 | 55 | 0.230 | 0.349 | 1.58 | 1B-CF-LF-RF |
| Jim Thome | 452 | 67 | 72 | 0.249 | 0.369 | 3.46 | DH |
| A.J. Pierzynski | 434 | 50 | 50 | 0.287 | 0.316 | -0.19 | CR |
| Paul Konerko | 387 | 42 | 42 | 0.224 | 0.328 | -0.72 | 1B |
| Joe Crede | 349 | 39 | 54 | 0.253 | 0.321 | 1.17 | 3B |
| Alexei Ramirez | 347 | 42 | 43 | 0.306 | 0.323 | 0.38 | 2B-SS-CF |
| Juan Uribe | 225 | 26 | 21 | 0.233 | 0.280 | -0.61 | 3B-2B |
| Brian Anderson | 155 | 15 | 21 | 0.241 | 0.277 | -0.04 | CF |
| Toby Hall | 102 | 7 | 5 | 0.277 | 0.324 | -1.25 | CR |
| Pablo Ozuna | 69 | 5 | 6 | 0.281 | 0.304 | -0.55 | 2B |
| Dewayne Wise | 68 | 9 | 6 | 0.281 | 0.309 | -0.10 | LF-CF |
| Ken Griffey | 37 | 3 | 3 | 0.219 | 0.324 | -0.28 | RF |
| Josh Fields | 25 | 2 | 2 | 0.182 | 0.280 | -0.20 | 3B |
| Chris Getz | 5 | 0 | 1 | 0.400 | 0.400 | -0.02 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Mark Buehrle | 162.3 | 3.77 | 25 | 0 | X | 1.84 |
| Javier Vazquez | 156.0 | 4.50 | 24 | 0 | X | -0.89 |
| Gavin Floyd | 146.3 | 3.75 | 24 | 0 | X | 1.72 |
| John Danks | 144.3 | 3.12 | 24 | 0 | X | 3.84 |
| Jose Contreras | 121.0 | 4.54 | 20 | 0 | X | -0.79 |
| Octavio Dotel | 54.7 | 3.29 | 0 | 58 | X | 1.23 |
| Matt Thornton | 50.0 | 2.88 | 0 | 54 | X | 1.61 |
| Nick Masset | 44.7 | 4.84 | 1 | 31 | X | -0.60 |
| Bobby Jenks | 43.3 | 1.87 | 0 | 43 | X | 2.41 |
| Boone Logan | 40.3 | 4.91 | 0 | 48 | X | -0.61 |
| Scott Linebrink | 39.0 | 2.31 | 0 | 42 | X | 1.77 |
| D.J. Carrasco | 23.0 | 2.74 | 0 | 15 | X | 0.81 |
| Adam Russell | 18.3 | 5.40 | 0 | 15 | X | -0.49 |
| Ehren Wassermann | 15.0 | 7.80 | 0 | 17 | X | -1.24 |
| Clayton Richard | 13.0 | 10.38 | 3 | 0 | X | -1.86 |
| Mike MacDougal | 8.7 | 2.08 | 0 | 8 | X | 0.44 |
| Lance Broadway | 5.7 | 3.18 | 1 | 1 | X | 0.14 |
| Horacio Ramirez | 3.3 | 5.40 | 0 | 4 | X | -0.09 |
| Esteban Loaiza | 3.0 | 3.00 | 0 | 3 | X | 0.09 |
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