| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Orlando Cabrera | 545 | 72 | 48 | 0.268 | 0.323 | -0.84 | SS |
| Carlos Quentin | 502 | 83 | 89 | 0.285 | 0.384 | 5.68 | LF |
| Jermaine Dye | 477 | 76 | 78 | 0.303 | 0.358 | 4.41 | RF |
| Nick Swisher | 469 | 71 | 55 | 0.232 | 0.350 | 1.67 | 1B-CF-LF-RF |
| Jim Thome | 448 | 67 | 71 | 0.249 | 0.371 | 3.44 | DH |
| A.J. Pierzynski | 430 | 49 | 49 | 0.285 | 0.314 | -0.31 | CR |
| Paul Konerko | 383 | 42 | 41 | 0.226 | 0.329 | -0.73 | 1B |
| Joe Crede | 349 | 39 | 54 | 0.253 | 0.321 | 1.16 | 3B |
| Alexei Ramirez | 343 | 42 | 43 | 0.304 | 0.321 | 0.47 | 2B-SS-CF |
| Juan Uribe | 221 | 26 | 21 | 0.238 | 0.285 | -0.51 | 3B-2B |
| Brian Anderson | 155 | 15 | 21 | 0.241 | 0.277 | -0.04 | CF |
| Toby Hall | 102 | 7 | 5 | 0.277 | 0.324 | -1.25 | CR |
| Pablo Ozuna | 69 | 5 | 6 | 0.281 | 0.304 | -0.55 | 2B |
| Dewayne Wise | 68 | 9 | 6 | 0.281 | 0.309 | -0.10 | LF-CF |
| Ken Griffey | 37 | 3 | 3 | 0.219 | 0.324 | -0.28 | RF |
| Josh Fields | 25 | 2 | 2 | 0.182 | 0.280 | -0.20 | 3B |
| Chris Getz | 5 | 0 | 1 | 0.400 | 0.400 | -0.02 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Mark Buehrle | 162.3 | 3.77 | 25 | 0 | X | 1.85 |
| Javier Vazquez | 156.0 | 4.50 | 24 | 0 | X | -0.88 |
| John Danks | 144.3 | 3.12 | 24 | 0 | X | 3.84 |
| Gavin Floyd | 140.7 | 3.84 | 23 | 0 | X | 1.38 |
| Jose Contreras | 121.0 | 4.54 | 20 | 0 | X | -0.78 |
| Octavio Dotel | 53.7 | 3.02 | 0 | 57 | X | 1.55 |
| Matt Thornton | 48.7 | 2.96 | 0 | 53 | X | 1.48 |
| Nick Masset | 44.7 | 4.84 | 1 | 31 | X | -0.60 |
| Bobby Jenks | 43.3 | 1.87 | 0 | 43 | X | 2.42 |
| Boone Logan | 40.3 | 4.91 | 0 | 48 | X | -0.61 |
| Scott Linebrink | 39.0 | 2.31 | 0 | 42 | X | 1.78 |
| D.J. Carrasco | 23.0 | 2.35 | 0 | 14 | X | 1.03 |
| Adam Russell | 18.3 | 5.40 | 0 | 15 | X | -0.49 |
| Ehren Wassermann | 15.0 | 7.80 | 0 | 17 | X | -1.24 |
| Clayton Richard | 13.0 | 10.38 | 3 | 0 | X | -1.86 |
| Mike MacDougal | 8.7 | 2.08 | 0 | 8 | X | 0.44 |
| Lance Broadway | 5.7 | 3.18 | 1 | 1 | X | 0.14 |
| Esteban Loaiza | 3.0 | 3.00 | 0 | 3 | X | 0.09 |
| Horacio Ramirez | 3.0 | 3.00 | 0 | 3 | X | 0.09 |
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