| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 530 | 81 | 54 | 0.315 | 0.357 | 1.39 | 2B |
| Kevin Youkilis | 461 | 69 | 76 | 0.315 | 0.384 | 4.11 | 1B-3B |
| Jacoby Ellsbury | 435 | 65 | 33 | 0.269 | 0.329 | -0.20 | CF-LF-RF |
| J.D. Drew | 427 | 75 | 60 | 0.283 | 0.412 | 3.88 | RF |
| Manny Ramirez | 425 | 68 | 70 | 0.299 | 0.398 | 4.24 | LF |
| Mike Lowell | 418 | 49 | 66 | 0.272 | 0.333 | 1.99 | 3B |
| Jason Varitek | 357 | 25 | 32 | 0.219 | 0.308 | -2.62 | CR |
| David Ortiz | 314 | 43 | 53 | 0.253 | 0.350 | 2.51 | DH |
| Julio Lugo | 307 | 27 | 22 | 0.268 | 0.352 | -2.26 | SS |
| Coco Crisp | 282 | 33 | 27 | 0.251 | 0.298 | -0.50 | CF |
| Sean Casey | 164 | 13 | 11 | 0.356 | 0.415 | -1.43 | 1B-DH |
| Jed Lowrie | 129 | 10 | 22 | 0.279 | 0.333 | 0.25 | SS-3B |
| Kevin Cash | 115 | 7 | 11 | 0.229 | 0.287 | -0.88 | CR |
| Alex Cora | 87 | 5 | 5 | 0.280 | 0.368 | -1.05 | SS |
| Brandon Moss | 86 | 7 | 11 | 0.295 | 0.337 | -0.18 | LF-RF |
| Jason Bay | 43 | 11 | 8 | 0.333 | 0.395 | 0.96 | LF |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.22 | X |
| Jeff Bailey | 8 | 1 | 0 | 0.000 | 0.375 | -0.09 | 1B |
| Chris Carter | 3 | 1 | 0 | 0.667 | 0.667 | 0.03 | X |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 153.3 | 3.23 | 24 | 0 | X | 3.78 |
| Tim Wakefield | 147.0 | 3.67 | 23 | 0 | X | 2.10 |
| Josh Beckett | 139.0 | 4.08 | 21 | 0 | X | 0.67 |
| Daisuke Matsuzaka | 114.7 | 2.90 | 20 | 0 | X | 3.69 |
| Clay Buchholz | 72.7 | 6.32 | 14 | 0 | X | -3.44 |
| Justin Masterson | 66.0 | 3.41 | 9 | 8 | X | 1.35 |
| Jonathan Papelbon | 49.3 | 2.01 | 0 | 48 | X | 2.62 |
| Manny Delcarmen | 48.7 | 4.07 | 0 | 52 | X | 0.25 |
| Hideki Okajima | 45.0 | 2.60 | 0 | 46 | X | 1.77 |
| Javier Lopez | 43.0 | 2.51 | 0 | 50 | X | 1.78 |
| David Aardsma | 40.7 | 2.88 | 0 | 39 | X | 1.34 |
| Bartolo Colon | 33.0 | 4.09 | 6 | 0 | X | 0.15 |
| Mike Timlin | 32.7 | 5.23 | 0 | 34 | X | -0.72 |
| Craig Hansen | 30.7 | 5.58 | 0 | 32 | X | -0.92 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.62 |
| Chris Smith | 8.3 | 2.16 | 0 | 5 | X | 0.41 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.87 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.67 |
_