| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 516 | 78 | 50 | 0.315 | 0.357 | 0.99 | 2B |
| Kevin Youkilis | 451 | 69 | 76 | 0.317 | 0.384 | 4.35 | 1B-3B |
| Manny Ramirez | 425 | 68 | 70 | 0.299 | 0.398 | 4.24 | LF |
| Jacoby Ellsbury | 422 | 61 | 29 | 0.261 | 0.322 | -0.73 | CF-LF-RF |
| J.D. Drew | 409 | 70 | 58 | 0.283 | 0.406 | 3.57 | RF |
| Mike Lowell | 400 | 48 | 63 | 0.277 | 0.340 | 2.01 | 3B |
| Jason Varitek | 345 | 23 | 32 | 0.220 | 0.310 | -2.55 | CR |
| Julio Lugo | 307 | 27 | 22 | 0.268 | 0.352 | -2.26 | SS |
| David Ortiz | 296 | 42 | 49 | 0.253 | 0.351 | 2.41 | DH |
| Coco Crisp | 279 | 33 | 27 | 0.250 | 0.297 | -0.43 | CF |
| Sean Casey | 155 | 12 | 11 | 0.355 | 0.413 | -1.32 | 1B-DH |
| Jed Lowrie | 113 | 9 | 20 | 0.289 | 0.336 | 0.32 | SS-3B |
| Kevin Cash | 111 | 7 | 11 | 0.228 | 0.288 | -0.79 | CR |
| Brandon Moss | 86 | 7 | 11 | 0.295 | 0.337 | -0.18 | LF-RF |
| Alex Cora | 81 | 4 | 5 | 0.271 | 0.358 | -1.01 | SS |
| Jason Bay | 25 | 8 | 6 | 0.429 | 0.520 | 0.87 | LF |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.22 | X |
| Jeff Bailey | 8 | 1 | 0 | 0.000 | 0.375 | -0.09 | 1B |
| Chris Carter | 3 | 1 | 0 | 0.667 | 0.667 | 0.03 | X |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 146.3 | 3.14 | 23 | 0 | X | 3.88 |
| Tim Wakefield | 141.0 | 3.77 | 22 | 0 | X | 1.67 |
| Josh Beckett | 139.0 | 4.08 | 21 | 0 | X | 0.63 |
| Daisuke Matsuzaka | 106.7 | 3.04 | 19 | 0 | X | 3.08 |
| Clay Buchholz | 69.7 | 5.94 | 13 | 0 | X | -2.71 |
| Justin Masterson | 62.3 | 3.61 | 9 | 6 | X | 0.97 |
| Jonathan Papelbon | 48.3 | 2.05 | 0 | 47 | X | 2.51 |
| Manny Delcarmen | 46.7 | 4.05 | 0 | 50 | X | 0.24 |
| Hideki Okajima | 44.0 | 2.66 | 0 | 45 | X | 1.66 |
| Javier Lopez | 43.0 | 2.51 | 0 | 50 | X | 1.77 |
| David Aardsma | 39.3 | 2.75 | 0 | 38 | X | 1.40 |
| Bartolo Colon | 33.0 | 4.09 | 6 | 0 | X | 0.14 |
| Mike Timlin | 31.7 | 5.12 | 0 | 33 | X | -0.62 |
| Craig Hansen | 30.7 | 5.58 | 0 | 32 | X | -0.93 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.63 |
| Chris Smith | 8.3 | 2.16 | 0 | 5 | X | 0.41 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.87 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.67 |
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