| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 511 | 77 | 48 | 0.316 | 0.358 | 0.81 | 2B |
| Kevin Youkilis | 446 | 68 | 76 | 0.316 | 0.383 | 4.37 | 1B-3B |
| Manny Ramirez | 425 | 68 | 70 | 0.299 | 0.398 | 4.25 | LF |
| Jacoby Ellsbury | 418 | 60 | 28 | 0.259 | 0.321 | -0.83 | CF-LF-RF |
| J.D. Drew | 404 | 70 | 58 | 0.283 | 0.403 | 3.70 | RF |
| Mike Lowell | 395 | 46 | 63 | 0.280 | 0.342 | 1.93 | 3B |
| Jason Varitek | 341 | 22 | 32 | 0.220 | 0.311 | -2.55 | CR |
| Julio Lugo | 307 | 27 | 22 | 0.268 | 0.352 | -2.25 | SS |
| David Ortiz | 291 | 42 | 48 | 0.254 | 0.354 | 2.44 | DH |
| Coco Crisp | 279 | 33 | 27 | 0.250 | 0.297 | -0.42 | CF |
| Sean Casey | 155 | 12 | 11 | 0.355 | 0.413 | -1.32 | 1B-DH |
| Kevin Cash | 111 | 7 | 11 | 0.228 | 0.288 | -0.78 | CR |
| Jed Lowrie | 108 | 9 | 18 | 0.293 | 0.343 | 0.23 | SS-3B |
| Brandon Moss | 86 | 7 | 11 | 0.295 | 0.337 | -0.18 | LF-RF |
| Alex Cora | 81 | 4 | 5 | 0.271 | 0.358 | -1.01 | SS |
| Jason Bay | 20 | 6 | 4 | 0.312 | 0.450 | 0.57 | LF |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.22 | X |
| Jeff Bailey | 8 | 1 | 0 | 0.000 | 0.375 | -0.09 | 1B |
| Chris Carter | 3 | 1 | 0 | 0.667 | 0.667 | 0.03 | X |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 146.3 | 3.14 | 23 | 0 | X | 3.85 |
| Tim Wakefield | 141.0 | 3.77 | 22 | 0 | X | 1.64 |
| Josh Beckett | 132.3 | 4.15 | 20 | 0 | X | 0.36 |
| Daisuke Matsuzaka | 106.7 | 3.04 | 19 | 0 | X | 3.05 |
| Clay Buchholz | 69.7 | 5.94 | 13 | 0 | X | -2.73 |
| Justin Masterson | 62.3 | 3.61 | 9 | 6 | X | 0.95 |
| Jonathan Papelbon | 48.3 | 2.05 | 0 | 47 | X | 2.50 |
| Manny Delcarmen | 46.7 | 4.05 | 0 | 50 | X | 0.23 |
| Hideki Okajima | 44.0 | 2.66 | 0 | 45 | X | 1.65 |
| Javier Lopez | 43.0 | 2.51 | 0 | 50 | X | 1.76 |
| David Aardsma | 39.3 | 2.75 | 0 | 38 | X | 1.39 |
| Bartolo Colon | 33.0 | 4.09 | 6 | 0 | X | 0.13 |
| Craig Hansen | 30.7 | 5.58 | 0 | 32 | X | -0.94 |
| Mike Timlin | 30.3 | 5.34 | 0 | 32 | X | -0.76 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.63 |
| Chris Smith | 7.3 | 2.45 | 0 | 4 | X | 0.31 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.87 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.67 |
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