| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 502 | 75 | 48 | 0.313 | 0.355 | 0.84 | 2B |
| Kevin Youkilis | 437 | 68 | 74 | 0.313 | 0.380 | 4.40 | 1B-3B |
| Manny Ramirez | 425 | 68 | 70 | 0.299 | 0.398 | 4.27 | LF |
| Jacoby Ellsbury | 415 | 60 | 28 | 0.258 | 0.320 | -0.74 | CF-LF-RF |
| J.D. Drew | 399 | 69 | 58 | 0.286 | 0.406 | 3.74 | RF |
| Mike Lowell | 391 | 45 | 63 | 0.281 | 0.343 | 1.93 | 3B |
| Jason Varitek | 333 | 22 | 32 | 0.220 | 0.306 | -2.34 | CR |
| Julio Lugo | 307 | 27 | 22 | 0.268 | 0.352 | -2.24 | SS |
| David Ortiz | 282 | 42 | 47 | 0.261 | 0.358 | 2.56 | DH |
| Coco Crisp | 271 | 32 | 25 | 0.252 | 0.303 | -0.53 | CF |
| Sean Casey | 150 | 12 | 11 | 0.360 | 0.420 | -1.19 | 1B-DH |
| Kevin Cash | 111 | 7 | 11 | 0.228 | 0.288 | -0.78 | CR |
| Jed Lowrie | 100 | 8 | 16 | 0.294 | 0.340 | 0.11 | SS-3B |
| Brandon Moss | 86 | 7 | 11 | 0.295 | 0.337 | -0.18 | LF-RF |
| Alex Cora | 81 | 4 | 5 | 0.271 | 0.358 | -1.00 | SS |
| Jason Bay | 11 | 4 | 3 | 0.286 | 0.545 | 0.47 | LF |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.22 | X |
| Jeff Bailey | 8 | 1 | 0 | 0.000 | 0.375 | -0.09 | 1B |
| Chris Carter | 3 | 1 | 0 | 0.667 | 0.667 | 0.03 | X |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 146.3 | 3.14 | 23 | 0 | X | 3.82 |
| Tim Wakefield | 141.0 | 3.77 | 22 | 0 | X | 1.61 |
| Josh Beckett | 132.3 | 4.15 | 20 | 0 | X | 0.33 |
| Daisuke Matsuzaka | 100.7 | 3.04 | 18 | 0 | X | 2.86 |
| Clay Buchholz | 63.7 | 5.94 | 12 | 0 | X | -2.50 |
| Justin Masterson | 61.3 | 3.67 | 9 | 5 | X | 0.84 |
| Jonathan Papelbon | 47.3 | 2.09 | 0 | 46 | X | 2.39 |
| Manny Delcarmen | 45.7 | 4.14 | 0 | 49 | X | 0.13 |
| Hideki Okajima | 43.0 | 2.72 | 0 | 44 | X | 1.54 |
| Javier Lopez | 42.0 | 2.57 | 0 | 49 | X | 1.65 |
| David Aardsma | 39.3 | 2.75 | 0 | 38 | X | 1.39 |
| Bartolo Colon | 33.0 | 4.09 | 6 | 0 | X | 0.13 |
| Craig Hansen | 30.7 | 5.58 | 0 | 32 | X | -0.94 |
| Mike Timlin | 30.3 | 5.34 | 0 | 32 | X | -0.77 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.63 |
| Chris Smith | 7.3 | 2.45 | 0 | 4 | X | 0.31 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.87 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.67 |
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