| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Orlando Cabrera | 489 | 65 | 44 | 0.267 | 0.323 | -0.56 | SS |
| Carlos Quentin | 455 | 76 | 82 | 0.283 | 0.380 | 5.42 | LF |
| Nick Swisher | 431 | 64 | 50 | 0.228 | 0.346 | 1.39 | 1B-CF-LF-RF |
| Jermaine Dye | 428 | 67 | 69 | 0.310 | 0.367 | 3.77 | RF |
| Jim Thome | 400 | 57 | 61 | 0.255 | 0.383 | 2.57 | DH |
| A.J. Pierzynski | 383 | 44 | 41 | 0.291 | 0.326 | -0.48 | CR |
| Joe Crede | 349 | 39 | 54 | 0.253 | 0.321 | 1.19 | 3B |
| Paul Konerko | 341 | 36 | 35 | 0.214 | 0.314 | -0.92 | 1B |
| Alexei Ramirez | 295 | 37 | 38 | 0.308 | 0.325 | 0.63 | 2B-SS-CF |
| Juan Uribe | 175 | 21 | 18 | 0.226 | 0.280 | -0.20 | 3B-2B |
| Brian Anderson | 148 | 12 | 19 | 0.230 | 0.264 | -0.38 | CF |
| Toby Hall | 90 | 6 | 4 | 0.280 | 0.333 | -1.16 | CR |
| Pablo Ozuna | 69 | 5 | 6 | 0.281 | 0.304 | -0.54 | 2B |
| Dewayne Wise | 58 | 8 | 5 | 0.296 | 0.328 | -0.06 | LF-CF |
| Josh Fields | 22 | 2 | 2 | 0.200 | 0.273 | -0.12 | 3B |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Mark Buehrle | 144.0 | 3.69 | 22 | 0 | X | 1.92 |
| Javier Vazquez | 135.0 | 4.73 | 21 | 0 | X | -1.49 |
| Gavin Floyd | 131.3 | 3.43 | 21 | 0 | X | 2.55 |
| John Danks | 130.7 | 3.24 | 22 | 0 | X | 3.11 |
| Jose Contreras | 119.3 | 4.60 | 19 | 0 | X | -0.95 |
| Octavio Dotel | 47.3 | 3.04 | 0 | 51 | X | 1.34 |
| Nick Masset | 44.7 | 4.84 | 1 | 31 | X | -0.60 |
| Matt Thornton | 42.7 | 2.53 | 0 | 48 | X | 1.72 |
| Scott Linebrink | 39.0 | 2.31 | 0 | 42 | X | 1.78 |
| Bobby Jenks | 37.3 | 2.17 | 0 | 37 | X | 1.82 |
| Boone Logan | 37.3 | 3.86 | 0 | 45 | X | 0.35 |
| D.J. Carrasco | 13.7 | 2.63 | 0 | 7 | X | 0.52 |
| Adam Russell | 9.7 | 5.59 | 0 | 9 | X | -0.30 |
| Ehren Wassermann | 9.0 | 9.00 | 0 | 13 | X | -1.00 |
| Mike MacDougal | 8.7 | 2.08 | 0 | 8 | X | 0.44 |
| Clayton Richard | 8.7 | 9.35 | 2 | 0 | X | -1.03 |
| Esteban Loaiza | 3.0 | 3.00 | 0 | 3 | X | 0.09 |
| Horacio Ramirez | 2.3 | 3.86 | 0 | 1 | X | 0.02 |
_