| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 491 | 73 | 48 | 0.313 | 0.354 | 0.84 | 2B |
| Kevin Youkilis | 426 | 66 | 70 | 0.309 | 0.378 | 3.99 | 1B-3B |
| Manny Ramirez | 425 | 68 | 70 | 0.299 | 0.398 | 4.22 | LF |
| Jacoby Ellsbury | 409 | 60 | 28 | 0.262 | 0.325 | -0.64 | CF-LF-RF |
| J.D. Drew | 389 | 68 | 58 | 0.283 | 0.401 | 3.83 | RF |
| Mike Lowell | 382 | 43 | 63 | 0.279 | 0.343 | 1.90 | 3B |
| Jason Varitek | 328 | 22 | 31 | 0.216 | 0.302 | -2.36 | CR |
| Julio Lugo | 307 | 27 | 22 | 0.268 | 0.352 | -2.27 | SS |
| David Ortiz | 272 | 41 | 47 | 0.266 | 0.360 | 2.67 | DH |
| Coco Crisp | 267 | 32 | 24 | 0.252 | 0.303 | -0.57 | CF |
| Sean Casey | 148 | 12 | 11 | 0.356 | 0.412 | -1.16 | 1B-DH |
| Kevin Cash | 108 | 7 | 11 | 0.235 | 0.296 | -0.72 | CR |
| Jed Lowrie | 90 | 6 | 11 | 0.269 | 0.322 | -0.39 | SS-3B |
| Brandon Moss | 86 | 7 | 11 | 0.295 | 0.337 | -0.19 | LF-RF |
| Alex Cora | 79 | 4 | 5 | 0.279 | 0.367 | -0.96 | SS |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.22 | X |
| Jeff Bailey | 8 | 1 | 0 | 0.000 | 0.375 | -0.09 | 1B |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Chris Carter | 3 | 1 | 0 | 0.667 | 0.667 | 0.03 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 139.3 | 3.17 | 22 | 0 | X | 3.60 |
| Tim Wakefield | 134.7 | 3.94 | 21 | 0 | X | 1.03 |
| Josh Beckett | 132.3 | 4.15 | 20 | 0 | X | 0.38 |
| Daisuke Matsuzaka | 100.7 | 3.04 | 18 | 0 | X | 2.89 |
| Clay Buchholz | 63.7 | 5.94 | 12 | 0 | X | -2.47 |
| Justin Masterson | 60.3 | 3.73 | 9 | 4 | X | 0.76 |
| Jonathan Papelbon | 45.3 | 2.18 | 0 | 45 | X | 2.21 |
| Manny Delcarmen | 45.0 | 4.20 | 0 | 48 | X | 0.08 |
| Hideki Okajima | 42.0 | 2.57 | 0 | 43 | X | 1.67 |
| Javier Lopez | 41.0 | 2.63 | 0 | 48 | X | 1.57 |
| David Aardsma | 39.3 | 2.75 | 0 | 38 | X | 1.40 |
| Bartolo Colon | 33.0 | 4.09 | 6 | 0 | X | 0.14 |
| Craig Hansen | 30.7 | 5.58 | 0 | 32 | X | -0.93 |
| Mike Timlin | 29.3 | 5.52 | 0 | 31 | X | -0.86 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.63 |
| Chris Smith | 6.3 | 2.84 | 0 | 3 | X | 0.21 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.87 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.67 |
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