| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 472 | 71 | 47 | 0.316 | 0.358 | 1.04 | 2B |
| Kevin Youkilis | 408 | 62 | 68 | 0.313 | 0.382 | 3.84 | 1B-3B |
| Manny Ramirez | 407 | 65 | 65 | 0.298 | 0.398 | 3.86 | LF |
| Jacoby Ellsbury | 398 | 59 | 27 | 0.259 | 0.324 | -0.54 | CF-LF-RF |
| J.D. Drew | 374 | 67 | 58 | 0.287 | 0.401 | 4.13 | RF |
| Mike Lowell | 365 | 43 | 61 | 0.285 | 0.351 | 2.14 | 3B |
| Jason Varitek | 313 | 21 | 30 | 0.215 | 0.297 | -2.17 | CR |
| Julio Lugo | 307 | 27 | 22 | 0.268 | 0.352 | -2.24 | SS |
| Coco Crisp | 263 | 31 | 22 | 0.248 | 0.300 | -0.76 | CF |
| David Ortiz | 254 | 37 | 44 | 0.257 | 0.354 | 2.40 | DH |
| Sean Casey | 148 | 12 | 11 | 0.356 | 0.412 | -1.14 | 1B-DH |
| Kevin Cash | 108 | 7 | 11 | 0.235 | 0.296 | -0.71 | CR |
| Brandon Moss | 86 | 7 | 11 | 0.295 | 0.337 | -0.18 | LF-RF |
| Jed Lowrie | 82 | 6 | 10 | 0.286 | 0.341 | -0.29 | SS-3B |
| Alex Cora | 72 | 3 | 5 | 0.279 | 0.375 | -0.89 | SS |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.22 | X |
| Jeff Bailey | 8 | 1 | 0 | 0.000 | 0.375 | -0.09 | 1B |
| Chris Carter | 3 | 1 | 0 | 0.667 | 0.667 | 0.03 | X |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Tim Wakefield | 134.7 | 3.94 | 21 | 0 | X | 0.99 |
| Jon Lester | 132.3 | 3.20 | 21 | 0 | X | 3.28 |
| Josh Beckett | 127.0 | 3.83 | 19 | 0 | X | 1.28 |
| Daisuke Matsuzaka | 95.7 | 2.63 | 17 | 0 | X | 3.62 |
| Clay Buchholz | 57.3 | 5.81 | 11 | 0 | X | -2.07 |
| Justin Masterson | 56.7 | 3.65 | 9 | 2 | X | 0.80 |
| Jonathan Papelbon | 44.3 | 2.23 | 0 | 44 | X | 2.09 |
| Manny Delcarmen | 42.3 | 4.46 | 0 | 46 | X | -0.20 |
| Hideki Okajima | 41.0 | 2.63 | 0 | 42 | X | 1.55 |
| Javier Lopez | 39.7 | 2.72 | 0 | 46 | X | 1.42 |
| David Aardsma | 39.3 | 2.75 | 0 | 38 | X | 1.39 |
| Bartolo Colon | 33.0 | 4.09 | 6 | 0 | X | 0.13 |
| Craig Hansen | 29.0 | 5.90 | 0 | 30 | X | -1.11 |
| Mike Timlin | 28.3 | 5.72 | 0 | 30 | X | -0.97 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.63 |
| Chris Smith | 6.3 | 2.84 | 0 | 3 | X | 0.21 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.87 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.67 |
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