| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 467 | 70 | 47 | 0.319 | 0.360 | 1.09 | 2B |
| Kevin Youkilis | 403 | 61 | 68 | 0.311 | 0.380 | 3.88 | 1B-3B |
| Manny Ramirez | 403 | 65 | 64 | 0.301 | 0.402 | 3.88 | LF |
| Jacoby Ellsbury | 398 | 59 | 27 | 0.259 | 0.324 | -0.51 | CF-LF-RF |
| J.D. Drew | 370 | 66 | 57 | 0.287 | 0.403 | 4.05 | RF |
| Mike Lowell | 361 | 43 | 61 | 0.287 | 0.352 | 2.27 | 3B |
| Jason Varitek | 313 | 21 | 30 | 0.215 | 0.297 | -2.15 | CR |
| Julio Lugo | 307 | 27 | 22 | 0.268 | 0.352 | -2.21 | SS |
| Coco Crisp | 259 | 31 | 22 | 0.252 | 0.305 | -0.64 | CF |
| David Ortiz | 250 | 37 | 43 | 0.252 | 0.352 | 2.41 | DH |
| Sean Casey | 148 | 12 | 11 | 0.356 | 0.412 | -1.13 | 1B-DH |
| Kevin Cash | 104 | 7 | 11 | 0.234 | 0.298 | -0.60 | CR |
| Brandon Moss | 86 | 7 | 11 | 0.295 | 0.337 | -0.17 | LF-RF |
| Jed Lowrie | 78 | 6 | 10 | 0.294 | 0.333 | -0.19 | SS-3B |
| Alex Cora | 72 | 3 | 5 | 0.279 | 0.375 | -0.89 | SS |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.22 | X |
| Jeff Bailey | 8 | 1 | 0 | 0.000 | 0.375 | -0.09 | 1B |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Chris Carter | 3 | 1 | 0 | 0.667 | 0.667 | 0.03 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 132.3 | 3.20 | 21 | 0 | X | 3.24 |
| Tim Wakefield | 129.3 | 3.69 | 20 | 0 | X | 1.68 |
| Josh Beckett | 127.0 | 3.83 | 19 | 0 | X | 1.24 |
| Daisuke Matsuzaka | 95.7 | 2.63 | 17 | 0 | X | 3.60 |
| Clay Buchholz | 57.3 | 5.81 | 11 | 0 | X | -2.09 |
| Justin Masterson | 56.7 | 3.49 | 9 | 1 | X | 0.99 |
| Jonathan Papelbon | 44.3 | 2.23 | 0 | 44 | X | 2.08 |
| Manny Delcarmen | 42.3 | 4.46 | 0 | 46 | X | -0.22 |
| Hideki Okajima | 41.0 | 2.63 | 0 | 42 | X | 1.54 |
| David Aardsma | 39.3 | 2.75 | 0 | 38 | X | 1.38 |
| Javier Lopez | 38.0 | 2.84 | 0 | 45 | X | 1.24 |
| Bartolo Colon | 33.0 | 4.09 | 6 | 0 | X | 0.12 |
| Craig Hansen | 28.3 | 5.08 | 0 | 29 | X | -0.55 |
| Mike Timlin | 27.0 | 6.00 | 0 | 29 | X | -1.11 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.64 |
| Chris Smith | 6.3 | 2.84 | 0 | 3 | X | 0.21 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.88 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.67 |
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