| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 447 | 68 | 47 | 0.321 | 0.360 | 1.34 | 2B |
| Manny Ramirez | 393 | 64 | 64 | 0.297 | 0.397 | 4.00 | LF |
| Kevin Youkilis | 384 | 58 | 67 | 0.314 | 0.380 | 3.90 | 1B-3B |
| Jacoby Ellsbury | 378 | 57 | 27 | 0.265 | 0.333 | -0.26 | CF-LF-RF |
| J.D. Drew | 350 | 64 | 55 | 0.294 | 0.406 | 4.09 | RF |
| Mike Lowell | 341 | 43 | 58 | 0.287 | 0.349 | 2.42 | 3B |
| Julio Lugo | 307 | 27 | 22 | 0.268 | 0.352 | -2.23 | SS |
| Jason Varitek | 295 | 20 | 28 | 0.214 | 0.298 | -2.04 | CR |
| David Ortiz | 246 | 37 | 43 | 0.252 | 0.354 | 2.49 | DH |
| Coco Crisp | 242 | 28 | 21 | 0.252 | 0.298 | -0.67 | CF |
| Sean Casey | 142 | 12 | 10 | 0.362 | 0.415 | -1.10 | 1B-DH |
| Kevin Cash | 104 | 7 | 11 | 0.234 | 0.298 | -0.61 | CR |
| Brandon Moss | 86 | 7 | 11 | 0.295 | 0.337 | -0.18 | LF-RF |
| Alex Cora | 72 | 3 | 5 | 0.279 | 0.375 | -0.89 | SS |
| Jed Lowrie | 61 | 6 | 7 | 0.278 | 0.311 | -0.10 | SS-3B |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.22 | X |
| Jeff Bailey | 8 | 1 | 0 | 0.000 | 0.375 | -0.09 | 1B |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Chris Carter | 3 | 1 | 0 | 0.667 | 0.667 | 0.03 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Tim Wakefield | 129.3 | 3.69 | 20 | 0 | X | 1.69 |
| Jon Lester | 125.0 | 3.38 | 20 | 0 | X | 2.52 |
| Josh Beckett | 120.0 | 3.97 | 18 | 0 | X | 0.77 |
| Daisuke Matsuzaka | 88.3 | 2.65 | 16 | 0 | X | 3.30 |
| Justin Masterson | 54.0 | 3.67 | 9 | 0 | X | 0.73 |
| Clay Buchholz | 52.0 | 5.88 | 10 | 0 | X | -1.98 |
| Jonathan Papelbon | 40.7 | 2.43 | 0 | 41 | X | 1.72 |
| Manny Delcarmen | 40.7 | 4.65 | 0 | 44 | X | -0.38 |
| David Aardsma | 39.3 | 2.75 | 0 | 38 | X | 1.38 |
| Hideki Okajima | 38.3 | 2.82 | 0 | 39 | X | 1.28 |
| Javier Lopez | 37.7 | 2.87 | 0 | 44 | X | 1.21 |
| Bartolo Colon | 33.0 | 4.09 | 6 | 0 | X | 0.12 |
| Craig Hansen | 27.3 | 5.27 | 0 | 28 | X | -0.65 |
| Mike Timlin | 27.0 | 6.00 | 0 | 29 | X | -1.10 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.63 |
| Chris Smith | 6.3 | 2.84 | 0 | 3 | X | 0.21 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.88 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.67 |
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