| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 443 | 67 | 47 | 0.317 | 0.357 | 1.35 | 2B |
| Manny Ramirez | 389 | 63 | 63 | 0.296 | 0.396 | 3.90 | LF |
| Kevin Youkilis | 380 | 58 | 67 | 0.316 | 0.382 | 4.01 | 1B-3B |
| Jacoby Ellsbury | 373 | 57 | 27 | 0.269 | 0.338 | -0.12 | CF-LF-RF |
| J.D. Drew | 346 | 64 | 55 | 0.298 | 0.410 | 4.20 | RF |
| Mike Lowell | 337 | 43 | 57 | 0.288 | 0.350 | 2.42 | 3B |
| Julio Lugo | 307 | 27 | 22 | 0.268 | 0.352 | -2.22 | SS |
| Jason Varitek | 295 | 20 | 28 | 0.214 | 0.298 | -2.03 | CR |
| David Ortiz | 246 | 37 | 43 | 0.252 | 0.354 | 2.50 | DH |
| Coco Crisp | 238 | 27 | 21 | 0.255 | 0.298 | -0.67 | CF |
| Sean Casey | 141 | 12 | 10 | 0.364 | 0.418 | -1.07 | 1B-DH |
| Kevin Cash | 101 | 7 | 11 | 0.242 | 0.307 | -0.53 | CR |
| Brandon Moss | 86 | 7 | 11 | 0.295 | 0.337 | -0.17 | LF-RF |
| Alex Cora | 72 | 3 | 5 | 0.279 | 0.375 | -0.89 | SS |
| Jed Lowrie | 57 | 6 | 7 | 0.275 | 0.298 | 0.00 | SS-3B |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.22 | X |
| Jeff Bailey | 8 | 1 | 0 | 0.000 | 0.375 | -0.09 | 1B |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Chris Carter | 3 | 1 | 0 | 0.667 | 0.667 | 0.03 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 125.0 | 3.38 | 20 | 0 | X | 2.49 |
| Tim Wakefield | 122.3 | 3.60 | 19 | 0 | X | 1.81 |
| Josh Beckett | 120.0 | 3.97 | 18 | 0 | X | 0.74 |
| Daisuke Matsuzaka | 88.3 | 2.65 | 16 | 0 | X | 3.27 |
| Justin Masterson | 54.0 | 3.67 | 9 | 0 | X | 0.72 |
| Clay Buchholz | 52.0 | 5.88 | 10 | 0 | X | -2.00 |
| Jonathan Papelbon | 40.7 | 2.43 | 0 | 41 | X | 1.71 |
| Manny Delcarmen | 39.7 | 4.54 | 0 | 43 | X | -0.28 |
| David Aardsma | 39.3 | 2.75 | 0 | 38 | X | 1.37 |
| Hideki Okajima | 38.3 | 2.82 | 0 | 39 | X | 1.27 |
| Javier Lopez | 37.7 | 2.87 | 0 | 44 | X | 1.20 |
| Bartolo Colon | 33.0 | 4.09 | 6 | 0 | X | 0.11 |
| Craig Hansen | 27.3 | 5.27 | 0 | 28 | X | -0.66 |
| Mike Timlin | 27.0 | 6.00 | 0 | 29 | X | -1.11 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.64 |
| Chris Smith | 6.3 | 2.84 | 0 | 3 | X | 0.21 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.88 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.68 |
_