| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 430 | 66 | 46 | 0.311 | 0.351 | 1.50 | 2B |
| Manny Ramirez | 376 | 60 | 62 | 0.292 | 0.388 | 3.84 | LF |
| Kevin Youkilis | 370 | 56 | 63 | 0.316 | 0.381 | 3.67 | 1B-3B |
| Jacoby Ellsbury | 359 | 57 | 27 | 0.276 | 0.343 | 0.25 | CF-LF-RF |
| J.D. Drew | 333 | 64 | 54 | 0.302 | 0.411 | 4.44 | RF |
| Mike Lowell | 324 | 43 | 57 | 0.301 | 0.364 | 2.77 | 3B |
| Julio Lugo | 307 | 27 | 22 | 0.268 | 0.352 | -2.18 | SS |
| Jason Varitek | 284 | 20 | 28 | 0.220 | 0.299 | -1.74 | CR |
| David Ortiz | 246 | 37 | 43 | 0.252 | 0.354 | 2.53 | DH |
| Coco Crisp | 234 | 27 | 21 | 0.259 | 0.303 | -0.54 | CF |
| Sean Casey | 134 | 11 | 10 | 0.363 | 0.410 | -0.99 | 1B-DH |
| Kevin Cash | 101 | 7 | 11 | 0.242 | 0.307 | -0.52 | CR |
| Brandon Moss | 86 | 7 | 11 | 0.295 | 0.337 | -0.16 | LF-RF |
| Alex Cora | 65 | 3 | 5 | 0.276 | 0.354 | -0.71 | SS |
| Jed Lowrie | 52 | 6 | 7 | 0.283 | 0.308 | 0.12 | SS-3B |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.21 | X |
| Jeff Bailey | 8 | 1 | 0 | 0.000 | 0.375 | -0.09 | 1B |
| Chris Carter | 3 | 1 | 0 | 0.667 | 0.667 | 0.03 | X |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 125.0 | 3.38 | 20 | 0 | X | 2.43 |
| Tim Wakefield | 122.3 | 3.60 | 19 | 0 | X | 1.75 |
| Josh Beckett | 112.0 | 3.94 | 17 | 0 | X | 0.73 |
| Daisuke Matsuzaka | 82.3 | 2.84 | 15 | 0 | X | 2.64 |
| Justin Masterson | 54.0 | 3.67 | 9 | 0 | X | 0.69 |
| Clay Buchholz | 47.3 | 5.70 | 9 | 0 | X | -1.64 |
| Jonathan Papelbon | 39.7 | 2.27 | 0 | 40 | X | 1.80 |
| David Aardsma | 39.0 | 2.77 | 0 | 37 | X | 1.32 |
| Manny Delcarmen | 38.3 | 4.70 | 0 | 42 | X | -0.43 |
| Hideki Okajima | 37.7 | 2.87 | 0 | 38 | X | 1.19 |
| Javier Lopez | 37.0 | 2.19 | 0 | 43 | X | 1.75 |
| Bartolo Colon | 33.0 | 4.09 | 6 | 0 | X | 0.10 |
| Craig Hansen | 26.3 | 5.47 | 0 | 27 | X | -0.77 |
| Mike Timlin | 25.7 | 6.31 | 0 | 28 | X | -1.25 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.64 |
| Chris Smith | 6.3 | 2.84 | 0 | 3 | X | 0.20 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.88 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.68 |
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