| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 425 | 65 | 44 | 0.310 | 0.351 | 1.32 | 2B |
| Manny Ramirez | 372 | 57 | 61 | 0.289 | 0.384 | 3.53 | LF |
| Kevin Youkilis | 365 | 55 | 57 | 0.314 | 0.381 | 3.06 | 1B-3B |
| Jacoby Ellsbury | 354 | 57 | 27 | 0.277 | 0.345 | 0.39 | CF-LF-RF |
| J.D. Drew | 328 | 61 | 53 | 0.298 | 0.405 | 4.16 | RF |
| Mike Lowell | 320 | 42 | 56 | 0.297 | 0.359 | 2.67 | 3B |
| Julio Lugo | 307 | 27 | 22 | 0.268 | 0.352 | -2.17 | SS |
| Jason Varitek | 284 | 20 | 28 | 0.220 | 0.299 | -1.73 | CR |
| David Ortiz | 246 | 37 | 43 | 0.252 | 0.354 | 2.54 | DH |
| Coco Crisp | 234 | 27 | 21 | 0.259 | 0.303 | -0.53 | CF |
| Sean Casey | 129 | 10 | 10 | 0.367 | 0.411 | -0.97 | 1B-DH |
| Kevin Cash | 97 | 6 | 11 | 0.241 | 0.309 | -0.53 | CR |
| Brandon Moss | 85 | 6 | 11 | 0.286 | 0.329 | -0.24 | LF-RF |
| Alex Cora | 64 | 3 | 4 | 0.263 | 0.344 | -0.79 | SS |
| Jed Lowrie | 48 | 6 | 7 | 0.310 | 0.333 | 0.22 | SS-3B |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.21 | X |
| Jeff Bailey | 8 | 1 | 0 | 0.000 | 0.375 | -0.09 | 1B |
| Chris Carter | 3 | 1 | 0 | 0.667 | 0.667 | 0.03 | X |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 125.0 | 3.38 | 20 | 0 | X | 2.40 |
| Tim Wakefield | 115.3 | 3.75 | 18 | 0 | X | 1.24 |
| Josh Beckett | 112.0 | 3.94 | 17 | 0 | X | 0.71 |
| Daisuke Matsuzaka | 82.3 | 2.84 | 15 | 0 | X | 2.62 |
| Justin Masterson | 54.0 | 3.67 | 9 | 0 | X | 0.68 |
| Clay Buchholz | 47.3 | 5.70 | 9 | 0 | X | -1.65 |
| Jonathan Papelbon | 39.7 | 2.27 | 0 | 40 | X | 1.79 |
| David Aardsma | 39.0 | 2.77 | 0 | 37 | X | 1.31 |
| Manny Delcarmen | 38.3 | 4.70 | 0 | 42 | X | -0.44 |
| Hideki Okajima | 37.7 | 2.87 | 0 | 38 | X | 1.18 |
| Javier Lopez | 37.0 | 2.19 | 0 | 43 | X | 1.74 |
| Bartolo Colon | 33.0 | 4.09 | 6 | 0 | X | 0.09 |
| Craig Hansen | 25.3 | 5.68 | 0 | 26 | X | -0.87 |
| Mike Timlin | 24.7 | 6.57 | 0 | 27 | X | -1.36 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.65 |
| Chris Smith | 6.3 | 2.84 | 0 | 3 | X | 0.20 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.88 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.68 |
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