| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 382 | 54 | 37 | 0.303 | 0.343 | 0.48 | 2B |
| Manny Ramirez | 336 | 50 | 54 | 0.283 | 0.375 | 2.94 | LF |
| Kevin Youkilis | 325 | 48 | 50 | 0.308 | 0.375 | 2.57 | 1B-3B |
| Jacoby Ellsbury | 311 | 52 | 24 | 0.275 | 0.347 | 0.59 | CF-LF-RF |
| J.D. Drew | 296 | 58 | 50 | 0.299 | 0.409 | 4.31 | RF |
| Mike Lowell | 281 | 38 | 47 | 0.299 | 0.359 | 2.25 | 3B |
| Julio Lugo | 275 | 23 | 18 | 0.269 | 0.356 | -2.23 | SS |
| Jason Varitek | 255 | 17 | 26 | 0.220 | 0.302 | -1.54 | CR |
| David Ortiz | 246 | 37 | 43 | 0.252 | 0.354 | 2.55 | DH |
| Coco Crisp | 214 | 24 | 21 | 0.270 | 0.308 | -0.36 | CF |
| Sean Casey | 115 | 7 | 8 | 0.358 | 0.409 | -1.16 | 1B-DH |
| Kevin Cash | 91 | 5 | 9 | 0.235 | 0.308 | -0.69 | CR |
| Brandon Moss | 68 | 5 | 8 | 0.262 | 0.324 | -0.25 | LF-RF |
| Alex Cora | 62 | 3 | 4 | 0.273 | 0.355 | -0.74 | SS |
| Jed Lowrie | 48 | 6 | 7 | 0.310 | 0.333 | 0.22 | SS-3B |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.21 | X |
| Jeff Bailey | 6 | 1 | 0 | 0.000 | 0.500 | -0.04 | 1B |
| Chris Carter | 3 | 1 | 0 | 0.667 | 0.667 | 0.03 | X |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Tim Wakefield | 109.0 | 3.72 | 17 | 0 | X | 1.21 |
| Jon Lester | 108.7 | 3.48 | 18 | 0 | X | 1.81 |
| Josh Beckett | 101.0 | 3.65 | 15 | 0 | X | 1.27 |
| Daisuke Matsuzaka | 70.0 | 3.21 | 13 | 0 | X | 1.60 |
| Justin Masterson | 48.0 | 3.75 | 8 | 0 | X | 0.49 |
| Clay Buchholz | 42.3 | 5.53 | 8 | 0 | X | -1.32 |
| David Aardsma | 37.0 | 2.92 | 0 | 34 | X | 1.10 |
| Jonathan Papelbon | 36.0 | 2.00 | 0 | 36 | X | 1.84 |
| Hideki Okajima | 34.3 | 3.15 | 0 | 34 | X | 0.84 |
| Manny Delcarmen | 34.3 | 3.93 | 0 | 37 | X | 0.21 |
| Bartolo Colon | 33.0 | 4.09 | 6 | 0 | X | 0.08 |
| Javier Lopez | 31.0 | 2.32 | 0 | 37 | X | 1.35 |
| Craig Hansen | 24.7 | 4.74 | 0 | 24 | X | -0.32 |
| Mike Timlin | 21.7 | 7.06 | 0 | 24 | X | -1.45 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.65 |
| Chris Smith | 6.3 | 2.84 | 0 | 3 | X | 0.20 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.88 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.63 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.68 |
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