| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 359 | 48 | 34 | 0.288 | 0.329 | 0.05 | 2B |
| Manny Ramirez | 314 | 47 | 51 | 0.291 | 0.379 | 2.80 | LF |
| Kevin Youkilis | 302 | 47 | 47 | 0.303 | 0.374 | 2.67 | 1B-3B |
| Jacoby Ellsbury | 292 | 50 | 23 | 0.275 | 0.349 | 0.70 | CF-LF-RF |
| J.D. Drew | 273 | 54 | 45 | 0.308 | 0.414 | 3.88 | RF |
| Julio Lugo | 259 | 21 | 18 | 0.274 | 0.363 | -2.08 | SS |
| Mike Lowell | 258 | 35 | 41 | 0.287 | 0.353 | 1.83 | 3B |
| David Ortiz | 246 | 37 | 43 | 0.252 | 0.354 | 2.53 | DH |
| Jason Varitek | 235 | 17 | 25 | 0.231 | 0.306 | -1.19 | CR |
| Coco Crisp | 209 | 22 | 21 | 0.271 | 0.306 | -0.47 | CF |
| Sean Casey | 113 | 7 | 8 | 0.365 | 0.416 | -1.12 | 1B-DH |
| Kevin Cash | 89 | 5 | 9 | 0.241 | 0.315 | -0.65 | CR |
| Brandon Moss | 59 | 5 | 7 | 0.226 | 0.288 | -0.15 | LF-RF |
| Alex Cora | 57 | 3 | 4 | 0.280 | 0.368 | -0.62 | SS |
| Jed Lowrie | 48 | 6 | 7 | 0.310 | 0.333 | 0.22 | SS-3B |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.21 | X |
| Jeff Bailey | 6 | 1 | 0 | 0.000 | 0.500 | -0.04 | 1B |
| Chris Carter | 3 | 1 | 0 | 0.667 | 0.667 | 0.03 | X |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 103.7 | 3.13 | 17 | 0 | X | 2.55 |
| Tim Wakefield | 102.0 | 3.88 | 16 | 0 | X | 0.71 |
| Josh Beckett | 94.0 | 3.73 | 14 | 0 | X | 0.98 |
| Daisuke Matsuzaka | 65.0 | 3.46 | 12 | 0 | X | 1.09 |
| Clay Buchholz | 42.3 | 5.53 | 8 | 0 | X | -1.33 |
| Justin Masterson | 42.0 | 3.43 | 7 | 0 | X | 0.74 |
| David Aardsma | 35.7 | 2.52 | 0 | 32 | X | 1.38 |
| Jonathan Papelbon | 34.7 | 2.08 | 0 | 35 | X | 1.70 |
| Bartolo Colon | 33.0 | 4.09 | 6 | 0 | X | 0.07 |
| Hideki Okajima | 33.0 | 3.00 | 0 | 32 | X | 0.91 |
| Manny Delcarmen | 32.0 | 3.38 | 0 | 34 | X | 0.60 |
| Javier Lopez | 29.3 | 2.45 | 0 | 36 | X | 1.18 |
| Craig Hansen | 22.0 | 4.91 | 0 | 21 | X | -0.37 |
| Mike Timlin | 21.7 | 7.06 | 0 | 24 | X | -1.46 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.65 |
| Chris Smith | 6.0 | 1.50 | 0 | 2 | X | 0.38 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.88 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.63 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.68 |
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