| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 346 | 46 | 32 | 0.281 | 0.324 | -0.06 | 2B |
| Manny Ramirez | 302 | 47 | 51 | 0.295 | 0.384 | 3.09 | LF |
| Kevin Youkilis | 297 | 47 | 47 | 0.305 | 0.377 | 2.79 | 1B-3B |
| Jacoby Ellsbury | 279 | 49 | 23 | 0.276 | 0.351 | 0.91 | CF-LF-RF |
| J.D. Drew | 265 | 54 | 44 | 0.318 | 0.426 | 3.97 | RF |
| Julio Lugo | 249 | 19 | 18 | 0.275 | 0.361 | -2.05 | SS |
| Mike Lowell | 246 | 31 | 39 | 0.277 | 0.341 | 1.49 | 3B |
| David Ortiz | 246 | 37 | 43 | 0.252 | 0.354 | 2.54 | DH |
| Jason Varitek | 227 | 17 | 24 | 0.230 | 0.308 | -1.11 | CR |
| Coco Crisp | 198 | 21 | 21 | 0.265 | 0.303 | -0.31 | CF |
| Sean Casey | 113 | 7 | 8 | 0.365 | 0.416 | -1.12 | 1B-DH |
| Kevin Cash | 85 | 4 | 6 | 0.237 | 0.306 | -0.98 | CR |
| Alex Cora | 57 | 3 | 4 | 0.280 | 0.368 | -0.62 | SS |
| Brandon Moss | 48 | 5 | 5 | 0.256 | 0.333 | -0.09 | LF-RF |
| Jed Lowrie | 48 | 6 | 7 | 0.310 | 0.333 | 0.22 | SS-3B |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.21 | X |
| Jeff Bailey | 6 | 1 | 0 | 0.000 | 0.500 | -0.04 | 1B |
| Chris Carter | 3 | 1 | 0 | 0.667 | 0.667 | 0.03 | X |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 103.7 | 3.13 | 17 | 0 | X | 2.59 |
| Tim Wakefield | 95.0 | 4.17 | 15 | 0 | X | 0.06 |
| Josh Beckett | 86.0 | 3.87 | 13 | 0 | X | 0.65 |
| Daisuke Matsuzaka | 65.0 | 3.46 | 12 | 0 | X | 1.11 |
| Clay Buchholz | 42.3 | 5.53 | 8 | 0 | X | -1.32 |
| Justin Masterson | 36.0 | 3.00 | 6 | 0 | X | 1.00 |
| David Aardsma | 34.7 | 2.60 | 0 | 31 | X | 1.29 |
| Jonathan Papelbon | 33.3 | 2.16 | 0 | 33 | X | 1.58 |
| Hideki Okajima | 33.0 | 3.00 | 0 | 32 | X | 0.92 |
| Bartolo Colon | 33.0 | 4.09 | 6 | 0 | X | 0.08 |
| Manny Delcarmen | 31.0 | 3.48 | 0 | 33 | X | 0.51 |
| Javier Lopez | 29.3 | 2.45 | 0 | 36 | X | 1.19 |
| Mike Timlin | 21.7 | 7.06 | 0 | 24 | X | -1.45 |
| Craig Hansen | 21.3 | 5.06 | 0 | 20 | X | -0.43 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.65 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.88 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.63 |
| Chris Smith | 4.0 | 2.25 | 0 | 1 | X | 0.18 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.68 |
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