| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 331 | 44 | 32 | 0.273 | 0.317 | 0.07 | 2B |
| Manny Ramirez | 289 | 46 | 50 | 0.295 | 0.381 | 3.17 | LF |
| Kevin Youkilis | 282 | 44 | 44 | 0.305 | 0.376 | 2.50 | 1B-3B |
| Jacoby Ellsbury | 264 | 48 | 23 | 0.281 | 0.360 | 1.15 | CF-LF-RF |
| J.D. Drew | 250 | 53 | 43 | 0.327 | 0.432 | 4.11 | RF |
| David Ortiz | 246 | 37 | 43 | 0.252 | 0.354 | 2.52 | DH |
| Julio Lugo | 242 | 18 | 15 | 0.275 | 0.364 | -2.32 | SS |
| Mike Lowell | 231 | 30 | 37 | 0.275 | 0.338 | 1.51 | 3B |
| Jason Varitek | 219 | 17 | 24 | 0.240 | 0.320 | -0.93 | CR |
| Coco Crisp | 189 | 20 | 21 | 0.260 | 0.296 | -0.21 | CF |
| Sean Casey | 111 | 7 | 8 | 0.373 | 0.423 | -1.08 | 1B-DH |
| Kevin Cash | 81 | 4 | 6 | 0.236 | 0.309 | -0.89 | CR |
| Alex Cora | 52 | 3 | 2 | 0.289 | 0.385 | -0.72 | SS |
| Jed Lowrie | 48 | 6 | 7 | 0.310 | 0.333 | 0.22 | SS-3B |
| Brandon Moss | 43 | 4 | 5 | 0.256 | 0.326 | -0.08 | LF-RF |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.22 | X |
| Jeff Bailey | 6 | 1 | 0 | 0.000 | 0.500 | -0.04 | 1B |
| Chris Carter | 3 | 1 | 0 | 0.667 | 0.667 | 0.03 | X |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 96.3 | 3.18 | 16 | 0 | X | 2.35 |
| Tim Wakefield | 88.0 | 4.19 | 14 | 0 | X | 0.06 |
| Josh Beckett | 86.0 | 3.87 | 13 | 0 | X | 0.70 |
| Daisuke Matsuzaka | 64.0 | 2.53 | 11 | 0 | X | 2.53 |
| Clay Buchholz | 42.3 | 5.53 | 8 | 0 | X | -1.29 |
| Justin Masterson | 36.0 | 3.00 | 6 | 0 | X | 1.03 |
| Bartolo Colon | 33.0 | 4.09 | 6 | 0 | X | 0.10 |
| David Aardsma | 32.7 | 2.76 | 0 | 29 | X | 1.12 |
| Jonathan Papelbon | 32.3 | 1.95 | 0 | 32 | X | 1.72 |
| Hideki Okajima | 30.3 | 2.97 | 0 | 30 | X | 0.89 |
| Manny Delcarmen | 30.3 | 3.56 | 0 | 32 | X | 0.47 |
| Javier Lopez | 26.7 | 2.36 | 0 | 34 | X | 1.16 |
| Mike Timlin | 21.7 | 7.06 | 0 | 24 | X | -1.44 |
| Craig Hansen | 18.7 | 5.79 | 0 | 18 | X | -0.68 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.64 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.88 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.68 |
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