| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 326 | 42 | 32 | 0.268 | 0.313 | -0.04 | 2B |
| Manny Ramirez | 289 | 46 | 50 | 0.295 | 0.381 | 3.16 | LF |
| Kevin Youkilis | 282 | 44 | 44 | 0.305 | 0.376 | 2.49 | 1B-3B |
| Jacoby Ellsbury | 259 | 47 | 23 | 0.283 | 0.363 | 1.15 | CF-LF-RF |
| David Ortiz | 246 | 37 | 43 | 0.252 | 0.354 | 2.51 | DH |
| J.D. Drew | 245 | 51 | 39 | 0.315 | 0.424 | 3.58 | RF |
| Julio Lugo | 237 | 18 | 15 | 0.276 | 0.363 | -2.21 | SS |
| Mike Lowell | 226 | 28 | 36 | 0.275 | 0.332 | 1.31 | 3B |
| Jason Varitek | 214 | 17 | 24 | 0.245 | 0.322 | -0.82 | CR |
| Coco Crisp | 188 | 20 | 21 | 0.262 | 0.298 | -0.20 | CF |
| Sean Casey | 106 | 7 | 8 | 0.371 | 0.425 | -0.96 | 1B-DH |
| Kevin Cash | 81 | 4 | 6 | 0.236 | 0.309 | -0.89 | CR |
| Alex Cora | 52 | 3 | 2 | 0.289 | 0.385 | -0.72 | SS |
| Jed Lowrie | 48 | 6 | 7 | 0.310 | 0.333 | 0.22 | SS-3B |
| Brandon Moss | 39 | 4 | 3 | 0.257 | 0.333 | -0.20 | LF-RF |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.22 | X |
| Jeff Bailey | 6 | 1 | 0 | 0.000 | 0.500 | -0.04 | 1B |
| Chris Carter | 3 | 1 | 0 | 0.667 | 0.667 | 0.03 | X |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 96.3 | 3.18 | 16 | 0 | X | 2.36 |
| Tim Wakefield | 88.0 | 4.19 | 14 | 0 | X | 0.07 |
| Josh Beckett | 86.0 | 3.87 | 13 | 0 | X | 0.71 |
| Daisuke Matsuzaka | 64.0 | 2.53 | 11 | 0 | X | 2.53 |
| Clay Buchholz | 42.3 | 5.53 | 8 | 0 | X | -1.29 |
| Bartolo Colon | 33.0 | 4.09 | 6 | 0 | X | 0.10 |
| David Aardsma | 32.7 | 2.76 | 0 | 29 | X | 1.12 |
| Jonathan Papelbon | 31.3 | 2.01 | 0 | 31 | X | 1.62 |
| Justin Masterson | 31.0 | 2.90 | 5 | 0 | X | 0.96 |
| Hideki Okajima | 30.3 | 2.97 | 0 | 30 | X | 0.89 |
| Manny Delcarmen | 28.3 | 3.81 | 0 | 31 | X | 0.27 |
| Javier Lopez | 25.7 | 2.45 | 0 | 33 | X | 1.06 |
| Mike Timlin | 21.7 | 7.06 | 0 | 24 | X | -1.43 |
| Craig Hansen | 18.7 | 4.82 | 0 | 17 | X | -0.26 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.64 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.88 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.68 |
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