| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 321 | 42 | 32 | 0.268 | 0.312 | 0.07 | 2B |
| Manny Ramirez | 285 | 46 | 50 | 0.296 | 0.382 | 3.25 | LF |
| Kevin Youkilis | 282 | 44 | 44 | 0.305 | 0.376 | 2.48 | 1B-3B |
| Jacoby Ellsbury | 258 | 47 | 23 | 0.284 | 0.364 | 1.16 | CF-LF-RF |
| David Ortiz | 246 | 37 | 43 | 0.252 | 0.354 | 2.50 | DH |
| J.D. Drew | 240 | 51 | 39 | 0.322 | 0.429 | 3.69 | RF |
| Julio Lugo | 232 | 18 | 14 | 0.275 | 0.358 | -2.20 | SS |
| Mike Lowell | 222 | 28 | 36 | 0.274 | 0.329 | 1.40 | 3B |
| Jason Varitek | 210 | 17 | 24 | 0.249 | 0.324 | -0.73 | CR |
| Coco Crisp | 184 | 18 | 19 | 0.256 | 0.293 | -0.53 | CF |
| Sean Casey | 102 | 6 | 8 | 0.372 | 0.422 | -0.98 | 1B-DH |
| Kevin Cash | 81 | 4 | 6 | 0.236 | 0.309 | -0.89 | CR |
| Alex Cora | 52 | 3 | 2 | 0.289 | 0.385 | -0.72 | SS |
| Jed Lowrie | 48 | 6 | 7 | 0.310 | 0.333 | 0.21 | SS-3B |
| Brandon Moss | 38 | 4 | 3 | 0.265 | 0.342 | -0.18 | LF-RF |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.22 | X |
| Jeff Bailey | 6 | 1 | 0 | 0.000 | 0.500 | -0.04 | 1B |
| Chris Carter | 3 | 1 | 0 | 0.667 | 0.667 | 0.03 | X |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 89.3 | 3.43 | 15 | 0 | X | 1.67 |
| Tim Wakefield | 88.0 | 4.19 | 14 | 0 | X | 0.07 |
| Josh Beckett | 86.0 | 3.87 | 13 | 0 | X | 0.72 |
| Daisuke Matsuzaka | 64.0 | 2.53 | 11 | 0 | X | 2.53 |
| Clay Buchholz | 42.3 | 5.53 | 8 | 0 | X | -1.28 |
| Bartolo Colon | 33.0 | 4.09 | 6 | 0 | X | 0.11 |
| David Aardsma | 32.7 | 2.76 | 0 | 29 | X | 1.12 |
| Justin Masterson | 31.0 | 2.90 | 5 | 0 | X | 0.96 |
| Jonathan Papelbon | 30.3 | 2.08 | 0 | 30 | X | 1.52 |
| Hideki Okajima | 29.3 | 3.07 | 0 | 29 | X | 0.79 |
| Manny Delcarmen | 28.3 | 3.81 | 0 | 31 | X | 0.28 |
| Javier Lopez | 25.7 | 2.45 | 0 | 33 | X | 1.06 |
| Mike Timlin | 21.7 | 7.06 | 0 | 24 | X | -1.43 |
| Craig Hansen | 18.7 | 4.82 | 0 | 17 | X | -0.26 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.64 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.88 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.68 |
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