| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 312 | 40 | 29 | 0.261 | 0.308 | -0.23 | 2B |
| Manny Ramirez | 281 | 46 | 50 | 0.301 | 0.388 | 3.35 | LF |
| Kevin Youkilis | 277 | 43 | 43 | 0.307 | 0.379 | 2.39 | 1B-3B |
| Jacoby Ellsbury | 249 | 45 | 22 | 0.282 | 0.365 | 1.07 | CF-LF-RF |
| David Ortiz | 246 | 37 | 43 | 0.252 | 0.354 | 2.51 | DH |
| J.D. Drew | 232 | 48 | 37 | 0.320 | 0.422 | 3.37 | RF |
| Julio Lugo | 225 | 18 | 14 | 0.268 | 0.351 | -2.03 | SS |
| Mike Lowell | 214 | 27 | 36 | 0.273 | 0.327 | 1.49 | 3B |
| Jason Varitek | 202 | 16 | 24 | 0.257 | 0.327 | -0.64 | CR |
| Coco Crisp | 179 | 17 | 15 | 0.252 | 0.291 | -0.93 | CF |
| Sean Casey | 97 | 6 | 8 | 0.371 | 0.423 | -0.85 | 1B-DH |
| Kevin Cash | 80 | 4 | 6 | 0.239 | 0.312 | -0.87 | CR |
| Alex Cora | 50 | 3 | 2 | 0.302 | 0.400 | -0.67 | SS |
| Jed Lowrie | 48 | 6 | 7 | 0.310 | 0.333 | 0.22 | SS-3B |
| Brandon Moss | 36 | 4 | 3 | 0.250 | 0.333 | -0.13 | LF-RF |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.22 | X |
| Jeff Bailey | 6 | 1 | 0 | 0.000 | 0.500 | -0.04 | 1B |
| Chris Carter | 3 | 1 | 0 | 0.667 | 0.667 | 0.03 | X |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 89.3 | 3.43 | 15 | 0 | X | 1.66 |
| Tim Wakefield | 88.0 | 4.19 | 14 | 0 | X | 0.06 |
| Josh Beckett | 79.0 | 4.22 | 12 | 0 | X | 0.01 |
| Daisuke Matsuzaka | 64.0 | 2.53 | 11 | 0 | X | 2.52 |
| Clay Buchholz | 42.3 | 5.53 | 8 | 0 | X | -1.29 |
| Justin Masterson | 31.0 | 2.90 | 5 | 0 | X | 0.95 |
| David Aardsma | 30.3 | 2.97 | 0 | 27 | X | 0.89 |
| Jonathan Papelbon | 30.3 | 2.08 | 0 | 30 | X | 1.52 |
| Bartolo Colon | 29.0 | 3.41 | 5 | 0 | X | 0.55 |
| Manny Delcarmen | 28.3 | 3.81 | 0 | 31 | X | 0.27 |
| Hideki Okajima | 28.3 | 3.18 | 0 | 28 | X | 0.69 |
| Javier Lopez | 24.7 | 2.55 | 0 | 32 | X | 0.96 |
| Mike Timlin | 20.0 | 5.85 | 0 | 22 | X | -0.76 |
| Craig Hansen | 18.7 | 4.82 | 0 | 17 | X | -0.26 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.64 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.88 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.68 |
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