| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 307 | 39 | 29 | 0.259 | 0.306 | -0.22 | 2B |
| Manny Ramirez | 280 | 46 | 50 | 0.302 | 0.389 | 3.36 | LF |
| Kevin Youkilis | 272 | 42 | 41 | 0.301 | 0.375 | 2.19 | 1B-3B |
| David Ortiz | 246 | 37 | 43 | 0.252 | 0.354 | 2.50 | DH |
| Jacoby Ellsbury | 244 | 44 | 22 | 0.279 | 0.365 | 1.08 | CF-LF-RF |
| J.D. Drew | 227 | 46 | 37 | 0.317 | 0.423 | 3.27 | RF |
| Julio Lugo | 225 | 18 | 14 | 0.268 | 0.351 | -2.04 | SS |
| Mike Lowell | 209 | 27 | 35 | 0.270 | 0.325 | 1.50 | 3B |
| Jason Varitek | 202 | 16 | 24 | 0.257 | 0.327 | -0.65 | CR |
| Coco Crisp | 174 | 16 | 14 | 0.253 | 0.293 | -1.02 | CF |
| Sean Casey | 97 | 6 | 8 | 0.371 | 0.423 | -0.86 | 1B-DH |
| Kevin Cash | 75 | 4 | 6 | 0.254 | 0.320 | -0.75 | CR |
| Jed Lowrie | 48 | 6 | 7 | 0.310 | 0.333 | 0.21 | SS-3B |
| Alex Cora | 45 | 3 | 2 | 0.300 | 0.378 | -0.55 | SS |
| Brandon Moss | 35 | 4 | 3 | 0.258 | 0.343 | -0.10 | LF-RF |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.22 | X |
| Jeff Bailey | 6 | 1 | 0 | 0.000 | 0.500 | -0.04 | 1B |
| Chris Carter | 3 | 1 | 0 | 0.667 | 0.667 | 0.03 | X |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 89.3 | 3.43 | 15 | 0 | X | 1.67 |
| Tim Wakefield | 81.0 | 4.33 | 13 | 0 | X | -0.21 |
| Josh Beckett | 79.0 | 4.22 | 12 | 0 | X | 0.02 |
| Daisuke Matsuzaka | 64.0 | 2.53 | 11 | 0 | X | 2.53 |
| Clay Buchholz | 42.3 | 5.53 | 8 | 0 | X | -1.29 |
| Justin Masterson | 31.0 | 2.90 | 5 | 0 | X | 0.96 |
| David Aardsma | 30.3 | 2.97 | 0 | 27 | X | 0.89 |
| Jonathan Papelbon | 29.3 | 1.84 | 0 | 29 | X | 1.63 |
| Bartolo Colon | 29.0 | 3.41 | 5 | 0 | X | 0.55 |
| Hideki Okajima | 28.0 | 2.89 | 0 | 27 | X | 0.87 |
| Manny Delcarmen | 27.7 | 3.90 | 0 | 30 | X | 0.21 |
| Javier Lopez | 24.7 | 2.55 | 0 | 32 | X | 0.96 |
| Mike Timlin | 20.0 | 5.85 | 0 | 22 | X | -0.76 |
| Craig Hansen | 17.7 | 5.09 | 0 | 16 | X | -0.36 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.64 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.88 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.68 |
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